Management of Pediatric Urinary Tract Infections: A Delphi Study
- PMID: 36009990
- PMCID: PMC9404756
- DOI: 10.3390/antibiotics11081122
Management of Pediatric Urinary Tract Infections: A Delphi Study
Abstract
Urinary tract infection (UTI) is one of the most common infectious diseases in the pediatric population and represents a major cause of antibiotic consumption and hospitalization in children. Considering the ongoing controversies on the management of pediatric UTI and the challenges due to increasing antimicrobial resistance, the aim of the present study was to evaluate the level of agreement on UTI management in pediatric age in Emilia-Romagna Region, Italy, and to assess on the basis of recent studies whether there is the need to change current recommendations used by primary care pediatricians, hospital pediatricians, and pediatric surgeons in everyday clinical practice to possibly improve outcomes. This consensus provides clear and shared indications on UTI management in pediatric age, based on the most updated literature. This work represents, in our opinion, the most complete and up-to-date collection of statements on procedures to follow for pediatric UTI, in order to guide physicians in the management of the patient, standardize approaches, and avoid abuse and misuse of antibiotics. Undoubtedly, more randomized and controlled trials are needed in the pediatric population to better define the best therapeutic management in cases with antimicrobial resistance and real usefulness of long-term antibiotic prophylaxis.
Keywords: antibiotic therapy; antimicrobial resistance; pediatric infectious diseases; pediatric urology; urinary tract infection; urine culture.
Conflict of interest statement
The authors declare no conflict of interest.
Similar articles
-
Antibiotic Prophylaxis for the Prevention of Urinary Tract Infections in Children: Guideline and Recommendations from the Emilia-Romagna Pediatric Urinary Tract Infections (UTI-Ped-ER) Study Group.Antibiotics (Basel). 2023 Jun 12;12(6):1040. doi: 10.3390/antibiotics12061040. Antibiotics (Basel). 2023. PMID: 37370359 Free PMC article. Review.
-
Swiss consensus recommendations on urinary tract infections in children.Eur J Pediatr. 2021 Mar;180(3):663-674. doi: 10.1007/s00431-020-03714-4. Epub 2020 Jul 3. Eur J Pediatr. 2021. PMID: 32621135 Free PMC article. Review.
-
Practice parameter: the diagnosis, treatment, and evaluation of the initial urinary tract infection in febrile infants and young children. American Academy of Pediatrics. Committee on Quality Improvement. Subcommittee on Urinary Tract Infection.Pediatrics. 1999 Apr;103(4 Pt 1):843-52. doi: 10.1542/peds.103.4.843. Pediatrics. 1999. PMID: 10103321
-
Urinary Tract Infection in Children: Management in the Era of Antibiotic Resistance-A Pediatric Urologist's View.Eur Urol Focus. 2017 Apr;3(2-3):207-211. doi: 10.1016/j.euf.2017.09.013. Epub 2017 Sep 29. Eur Urol Focus. 2017. PMID: 28965960 Review.
-
Non-antibiotic interventions for prevention of urinary tract infections in children: a systematic review and meta-analysis of randomized controlled trials.Eur J Pediatr. 2021 Dec;180(12):3535-3545. doi: 10.1007/s00431-021-04091-2. Epub 2021 Jun 22. Eur J Pediatr. 2021. PMID: 34156540
Cited by
-
Antibiotic-Resistant Pseudomonas aeruginosa: Current Challenges and Emerging Alternative Therapies.Microorganisms. 2025 Apr 16;13(4):913. doi: 10.3390/microorganisms13040913. Microorganisms. 2025. PMID: 40284749 Free PMC article. Review.
-
Infections in Children with Cancer Admitted in an Oncology Reference Hospital: A Cross-sectional Study.Curr Microbiol. 2023 Aug 7;80(9):315. doi: 10.1007/s00284-023-03420-y. Curr Microbiol. 2023. PMID: 37544971
-
Antibiotic Prophylaxis for the Prevention of Urinary Tract Infections in Children: Guideline and Recommendations from the Emilia-Romagna Pediatric Urinary Tract Infections (UTI-Ped-ER) Study Group.Antibiotics (Basel). 2023 Jun 12;12(6):1040. doi: 10.3390/antibiotics12061040. Antibiotics (Basel). 2023. PMID: 37370359 Free PMC article. Review.
-
Clinical Outcomes of Voiding Cystourethrogram and Antibiotic Prophylaxis.Cureus. 2023 Oct 10;15(10):e46814. doi: 10.7759/cureus.46814. eCollection 2023 Oct. Cureus. 2023. PMID: 37954724 Free PMC article.
-
Guidelines for Complicated Urinary Tract Infections in Children: A Review by the European Society for Pediatric Infectious Diseases.Pediatr Infect Dis J. 2025 Jun 1;44(6):e211-e223. doi: 10.1097/INF.0000000000004790. Epub 2025 Mar 19. Pediatr Infect Dis J. 2025. PMID: 40106750 Free PMC article. Review.
References
LinkOut - more resources
Full Text Sources