Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?
- PMID: 36010011
- PMCID: PMC9406656
- DOI: 10.3390/children9081120
Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?
Abstract
Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and long-lasting solutions as TB is one of the top ten causes of ill health and death in children as well as adolescents universally. Minors are particularly susceptible to this severe illness that can be fatal post-infection or even serve as reservoirs for future disease outbreaks. However, pediatric TB is the least prioritized in most health programs and optimal infection/disease control has been quite neglected for this specialized patient category, as most scientific and clinical research efforts focus on developing novel management strategies for adults. Moreover, the ongoing coronavirus pandemic has meaningfully hindered the gains and progress achieved with TB prophylaxis, therapy, diagnosis, and global eradication goals for all affected persons of varying age bands. Thus, the opening of novel research activities and opportunities that can provide more insight and create new knowledge specifically geared towards managing TB disease in this specialized group will significantly improve their well-being and longevity.
Keywords: COVID-19; coronavirus pandemic; diagnosis; extrapulmonary tuberculosis; pediatrics; prevention; pulmonary tuberculosis; treatment.
Conflict of interest statement
The authors declare no conflict of interest.
Similar articles
-
[Development of antituberculous drugs: current status and future prospects].Kekkaku. 2006 Dec;81(12):753-74. Kekkaku. 2006. PMID: 17240921 Review. Japanese.
-
Recommendations for prevention and control of tuberculosis among foreign-born persons. Report of the Working Group on Tuberculosis among Foreign-Born Persons. Centers for Disease Control and Prevention.MMWR Recomm Rep. 1998 Sep 18;47(RR-16):1-29. MMWR Recomm Rep. 1998. PMID: 9760223
-
Challenges and opportunities for eliminating tuberculosis - leveraging political momentum of the UN high-level meeting on tuberculosis.BMC Public Health. 2019 Jan 16;19(1):76. doi: 10.1186/s12889-019-6399-8. BMC Public Health. 2019. PMID: 30651096 Free PMC article.
-
Demographic profile, clinical and microbiological predictors of mortality amongst admitted pediatric TB patients in a tertiary referral tuberculosis hospital.Indian J Tuberc. 2020 Jul;67(3):312-319. doi: 10.1016/j.ijtb.2019.10.001. Epub 2019 Oct 21. Indian J Tuberc. 2020. PMID: 32825857
-
Treatment of Rifampicin-Resistant Tuberculosis Disease and Infection in Children: Key Updates, Challenges and Opportunities.Pathogens. 2022 Mar 23;11(4):381. doi: 10.3390/pathogens11040381. Pathogens. 2022. PMID: 35456056 Free PMC article. Review.
Cited by
-
Pharmaceutical cost dynamics for the treatment of rifampicin-resistant tuberculosis in children and adolescents in South Africa, India, and the Philippines.PLoS One. 2024 Jul 23;19(7):e0305930. doi: 10.1371/journal.pone.0305930. eCollection 2024. PLoS One. 2024. PMID: 39042708 Free PMC article. Clinical Trial.
-
Disseminated tuberculosis in a migrant child.BMJ Case Rep. 2024 Feb 20;17(2):e259295. doi: 10.1136/bcr-2023-259295. BMJ Case Rep. 2024. PMID: 38378592
-
Leading Paediatric Infectious Diseases-Current Trends, Gaps, and Future Prospects in Oral Pharmacotherapeutic Interventions.Pharmaceutics. 2024 May 26;16(6):712. doi: 10.3390/pharmaceutics16060712. Pharmaceutics. 2024. PMID: 38931836 Free PMC article. Review.
-
A critical perspective on paediatric pulmonary tuberculosis and diagnostic advancements.Afr J Thorac Crit Care Med. 2024 Dec 11;30(4):e2883. doi: 10.7196/AJTCCM.2024.v30i4.2883. eCollection 2024. Afr J Thorac Crit Care Med. 2024. PMID: 40041415 Free PMC article. No abstract available.
-
Comparison of chest ultrasound features to chest radiography in the diagnosis for pediatric tuberculosis: a cross-sectional study.Pan Afr Med J. 2024 Nov 27;49:95. doi: 10.11604/pamj.2024.49.95.45265. eCollection 2024. Pan Afr Med J. 2024. PMID: 40060286 Free PMC article.
References
-
- World Health Organization . Tuberculosis Global Report. World Health Organization; Geneva, Switzerland: 2021.
-
- World Health Organization . State of Inequality: HIV, Tuberculosis and Malaria. World Health Organization; Geneva, Switzerland: 2021.
Publication types
Grants and funding
LinkOut - more resources
Full Text Sources