Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Aug 9;11(16):2387.
doi: 10.3390/foods11162387.

A2 Milk: New Perspectives for Food Technology and Human Health

Affiliations
Review

A2 Milk: New Perspectives for Food Technology and Human Health

Salvador Fernández-Rico et al. Foods. .

Abstract

Although milk consumption is increasing worldwide, in some geographical regions, its consumption has persistently declined in recent decades. This fact, together with the increase in milk production prices, has caused both milk producers and the dairy industry to be immersed in a major crisis. Some possible solutions to this problem are to get people who do not currently consume milk to start drinking it again, or to market milk and dairy products with a higher added value. In this context, a type of milk called A2 has recently received attention from the industry. This type of milk, characterized by a difference in an amino acid at position 67 of the β-casein polypeptide chain, releases much smaller amounts of bioactive opioid peptide β-casomorphin 7 upon digestion, which has been linked to harmful effects on human health. Additionally, A2 milk has been attributed worse technological properties in the production of some dairy products. Thus, doubts exist about the convenience for the dairy industry to bet on this product. The aim of this review is to provide an update on the effects on human health of A2 milk, as well as its different technological properties to produce dairy products.

Keywords: A2 milk; gastrointestinal discomfort; lactose intolerance; β-casein; β-casomorphin 7.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Rasika D.M.D., Vidanarachchi J.V., Silva Rocha R., Balthazar C.F., Cruz A.G., Sant’Ana J.S., Ranadheera C.S. Plant-based milk substitutes as emerging probiotic carriers. Curr. Opin. Food Sci. 2021;38:8–20. doi: 10.1016/j.cofs.2020.10.025. - DOI
    1. Beldycka-Bórawska A., Bórawski P., Guth M., Parzonko A., Rokicki T., Klepacki B., Wysokinski M., Maciag A., Dunn J.W. Price changes of dairy products in the european union. Agric. Econ. 2021;67:373–381. doi: 10.17221/61/2021-AGRICECON. - DOI
    1. Pouch T., Trouvé A. Deregulation and the crisis of dairy markets in Europe: Facts for economic interpretation. Stud. Political Econ. 2018;99:194–212. doi: 10.1080/07078552.2018.1492216. - DOI
    1. Storhaug C.L., Fosse S.K., Fadnes L.T. Country, regional, and global estimates for lactose malabsorption in adults: A systematic review and meta-analysis. Lancet Gastroenterol. Hepatol. 2017;2:738–746. doi: 10.1016/S2468-1253(17)30154-1. - DOI - PubMed
    1. Semwal R., Kumar Joshi S., Badoni Semwal R., Sodhi M., Upadhyaya K., Semwal D.K. Effects of A1 and A2 variants of β-casein on human health-is β-casomorphin-7 truly a harmful peptide in cow milk? Nutrire. 2022;47:8. doi: 10.1186/s41110-022-00159-7. - DOI

LinkOut - more resources