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Review
. 2022 Aug 22;11(8):951.
doi: 10.3390/pathogens11080951.

Pathogenicity Factors of Botryosphaeriaceae Associated with Grapevine Trunk Diseases: New Developments on Their Action on Grapevine Defense Responses

Marie Belair  1 , Alexia Laura Grau  2 , Julie Chong  2 , Xubin Tian  3   4 , Jiaxin Luo  3   4 , Xin Guan  3   4 , Flora Pensec  1
Affiliations
Review

Pathogenicity Factors of Botryosphaeriaceae Associated with Grapevine Trunk Diseases: New Developments on Their Action on Grapevine Defense Responses

Marie Belair et al. Pathogens. .

Abstract

Botryosphaeriaceae are a family of fungi associated with the decay of a large number of woody plants with economic importance and causing particularly great losses in viticulture due to grapevine trunk diseases. In recent years, major advances in the knowledge of the pathogenicity factors of these pathogens have been made possible by the development of next-generation sequencing. This review highlights the knowledge gained on genes encoding small secreted proteins such as effectors, carbohydrate-associated enzymes, transporters and genes associated with secondary metabolism, their representativeness within the Botryosphaeriaceae family and their expression during grapevine infection. These pathogenicity factors are particularly expressed during host-pathogen interactions, facilitating fungal development and nutrition, wood colonization, as well as manipulating defense pathways and inducing impacts at the cellular level and phytotoxicity. This work highlights the need for further research to continue the effort to elucidate the pathogenicity mechanisms of this family of fungi infecting grapevine in order to improve the development of control methods and varietal resistance and to reduce the development and the effects of the disease on grapevine harvest quality and yield.

Keywords: Botryosphaeriaceae; dieback; grapevine; pathogenicity factors; plant defense response; trunk diseases.

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Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Batista E., Lopes A., Alves A. Botryosphaeriaceae Species on Forest Trees in Portugal: Diversity, Distribution and Pathogenicity. Eur. J. Plant Pathol. 2020;158:693–720. doi: 10.1007/s10658-020-02112-8. - DOI
    1. Mehl J.W.M., Slippers B., Roux J., Wingfield M.J. Overlap of Latent Pathogens in the Botryosphaeriaceae on a Native and Agricultural Host. Fungal Biol. 2017;121:405–419. doi: 10.1016/j.funbio.2016.07.015. - DOI - PubMed
    1. Marsberg A., Kemler M., Jami F., Nagel J.H., Postma-Smidt A., Naidoo S., Wingfield M.J., Crous P.W., Spatafora J.W., Hesse C.N., et al. Botryosphaeria dothidea: A Latent Pathogen of Global Importance to Woody Plant Health. Mol. Plant Pathol. 2017;18:477–488. doi: 10.1111/mpp.12495. - DOI - PMC - PubMed
    1. Linaldeddu B.T., Deidda A., Scanu B., Franceschini A., Serra S., Berraf-Tebbal A., Zouaoui Boutiti M., Ben Jamâa M.L., Phillips A.J.L. Diversity of Botryosphaeriaceae Species Associated with Grapevine and Other Woody Hosts in Italy, Algeria and Tunisia, with Descriptions of Lasiodiplodia exigua and Lasiodiplodia mediterranea Sp. Nov. Fungal Divers. 2015;71:201–214. doi: 10.1007/s13225-014-0301-x. - DOI
    1. Nagel J.H., Wingfield M.J., Slippers B. Next-Generation Sequencing Provides Important Insights into the Biology and Evolution of the Botryosphaeriaceae. Fungal Biol. Rev. 2021;38:25–43. doi: 10.1016/j.fbr.2021.09.002. - DOI

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