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. 2022 Aug 18;15(8):1273-1278.
doi: 10.18240/ijo.2022.08.08. eCollection 2022.

Outcomes of chronic angle-closure glaucoma treated by phacoemulsification and endocyclophotocoagulation with or without endoscopically goniosynechialysis

Affiliations

Outcomes of chronic angle-closure glaucoma treated by phacoemulsification and endocyclophotocoagulation with or without endoscopically goniosynechialysis

Xing Wu et al. Int J Ophthalmol. .

Erratum in

  • CORRIGENDUM.
    [No authors listed] [No authors listed] Int J Ophthalmol. 2022 Sep 18;15(9):1537. eCollection 2022. Int J Ophthalmol. 2022. PMID: 36124181 Free PMC article.

Abstract

Aim: To investigate the surgical outcomes of patients with chronic angle-closure glaucoma (CACG) treated with phacoemulsification (phaco)/endocyclophotocoagulation (ECP) with and without endoscopic goniosynechialysis (E-GSL).

Methods: A retrospective, nonrandomized, comparative case series was conducted. Patients with CACG who underwent phaco in combination with either ECP alone (ECP group) or GSL with ECP (E-GSL group) from 2018 to 2019 were followed for 12mo and reviewed. Clinical features and outcomes were identified and analyzed. The ECP and E-GSL groups were matched in age and baseline intraocular pressure (IOP). Changes in IOP, mean of visual acuity (VA), peripheral anterior synechiae (PAS) formation, and the number of glaucoma medications was examined.

Results: The ECP group included 32 eyes of 27 patients, and the E-GSL group included 32 eyes of 26 patients. The preoperative baseline IOP was 22.18±6.48 mm Hg in the ECP group and 22.95±6.71 mm Hg in the E-GSL group (P=0.644). The mean IOP reduction was 26.2% in the ECP group and 41.6% in the E-GSL group at 12mo. The mean postoperative VA (logMAR units) at 12mo was 0.47 in the ECP group and 0.36 in the E-GSL group. The reduction in PAS formation and the number of glaucoma medications was also higher in the ECP group than E-GSL group at 12mo.

Conclusion: The phaco/ECP and phaco/E-GSL groups both achieve a significant reduction in IOP without complications associated with traditional glaucoma filtration surgeries.

Keywords: chronic angle-closure glaucoma; endocyclophotocoagulation; goniosynechialysis; phacoemulsification.

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Figures

Figure 1
Figure 1. Change in IOP postoperatively
aP<0.05, bP<0.01, cP<0.001 vs ECP; eP<0.01, fP<0.001 vs baseline. ECP: Endocyclophotocoagulation; E-GSL: Endoscopic goniosynechialysis.
Figure 2
Figure 2. Change in VA (logMAR) preoperatively and postoperatively
dP<0.05, eP<0.01, fP<0.001 vs baseline.

References

    1. Marchini G, Chemello F, Berzaghi D, Zampieri A. New findings in the diagnosis and treatment of primary angle-closure glaucoma. Prog Brain Res. 2015;221:191–212. - PubMed
    1. Young C, Seibold LK, Kahook MY. Cataract surgery and intraocular pressure in glaucoma. Curr Opin Ophthalmol. 2020;31(1):15–22. - PubMed
    1. Sun XH, Dai Y, Chen YH, Yu DY, Cringle SJ, Chen JY, Kong XM, Wang XL, Jiang CH. Primary angle closure glaucoma: what we know and what we don't know. Prog Retin Eye Res. 2017;57:26–45. - PubMed
    1. Chen PP, Lin SC, Junk AK, Radhakrishnan S, Singh K, Chen TC. The effect of phacoemulsification on intraocular pressure in glaucoma patients. Ophthalmology. 2015;122(7):1294–1307. - PubMed
    1. Azuara-Blanco A, Burr J, Ramsay C, Cooper D, Foster PJ, Friedman DS, Scotland G, Javanbakht M, Cochrane C, Norrie J. Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial. Lancet. 2016;388(10052):1389–1397. - PubMed

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