Clinical Trial
doi: 10.1055/s-0028-1094526.
Three double-blind comparative trials of mianserine (ORG GB 94) and amitriptyline in the treatment of depressive illness
- PMID: 360231
- DOI: 10.1055/s-0028-1094526
Item in Clipboard
Clinical Trial
Three double-blind comparative trials of mianserine (ORG GB 94) and amitriptyline in the treatment of depressive illness
Pharmakopsychiatr Neuropsychopharmakol.
1977 Mar.
Abstract
The results of double-blind comparative trials carried out simultaneously in three Finnish hospitals are presented. The antidepressant activity and side-effects of mianserine (ORG GB 94) and amitriptyline were compared. No statistically significant differences were found between the two treatments. It was found, however, that mianserine had clearly less anticholinergic side-effects than amitriptyline.
Similar articles
-
Mianserin: a review of its pharmacological properties and therapeutic efficacy in depressive illness.Drugs. 1978 Oct;16(4):273-301. doi: 10.2165/00003495-197816040-00001. Drugs. 1978. PMID: 359311 Review.
-
A double blind comparative study of mianserin and a fixed combination of amitriptyline plus chlordiazepoxide.Adv Biochem Psychopharmacol. 1982;32:213-22. Adv Biochem Psychopharmacol. 1982. PMID: 7046365 Clinical Trial.
-
Mianserin versus amitriptyline. A double-blind-trial evaluated by the AMP system.Int Pharmacopsychiatry. 1976;11(1):25-31. Int Pharmacopsychiatry. 1976. PMID: 770364 Clinical Trial.
-
Treatment of severe depressive illness: a double-blind comparison of mianserin and long-acting amitriptyline.Br J Clin Pract. 1982 Jun;36(6):240-2. Br J Clin Pract. 1982. PMID: 6756455 Clinical Trial. No abstract available.
-
Mianserin: result of a decade of antidepressant research.Pharm Weekbl Sci. 1982 Oct 22;4(5):139-45. doi: 10.1007/BF01959033. Pharm Weekbl Sci. 1982. PMID: 6128715 Review.
Cited by
-
Amitriptyline for depression.Cochrane Database Syst Rev. 2007 Jul 18;2007(3):CD004186. doi: 10.1002/14651858.CD004186.pub2. Cochrane Database Syst Rev. 2007. PMID: 17636748 Free PMC article.
-
Mianserin: a review of its pharmacological properties and therapeutic efficacy in depressive illness.Drugs. 1978 Oct;16(4):273-301. doi: 10.2165/00003495-197816040-00001. Drugs. 1978. PMID: 359311 Review.
-
Mianserin in the treatment of depressive illness: A comparison with amitriptyline.Ir J Med Sci. 1979 Dec;148(1):145. doi: 10.1007/BF02938068. Ir J Med Sci. 1979. PMID: 27517406
-
Prejudices in pharmacology and pharmacotherapy. The so-called anticholinergic effect of antidepressants.Agents Actions. 1977 Sep;7(3):313-5. doi: 10.1007/BF01969561. Agents Actions. 1977. PMID: 596314
-
Clinical study of mianserin, imipramine and placebo in depression: blood level and MHPG correlations.Br J Clin Pharmacol. 1978;5 Suppl 1(Suppl 1):35S-41S. Br J Clin Pharmacol. 1978. PMID: 341942 Free PMC article. Clinical Trial.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
