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Clinical Trial
. 1977 Mar;10(2):101-3.
doi: 10.1055/s-0028-1094526.

Three double-blind comparative trials of mianserine (ORG GB 94) and amitriptyline in the treatment of depressive illness

M O Jaskari, U G Ahfors, L Ginman, K Lydekcne, P Tienari
Clinical Trial

Three double-blind comparative trials of mianserine (ORG GB 94) and amitriptyline in the treatment of depressive illness

M O Jaskari et al. Pharmakopsychiatr Neuropsychopharmakol. 1977 Mar.

Abstract

The results of double-blind comparative trials carried out simultaneously in three Finnish hospitals are presented. The antidepressant activity and side-effects of mianserine (ORG GB 94) and amitriptyline were compared. No statistically significant differences were found between the two treatments. It was found, however, that mianserine had clearly less anticholinergic side-effects than amitriptyline.

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