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Case Reports
. 2022 Aug 26;22(1):322.
doi: 10.1186/s12883-022-02834-8.

Acute dizziness and mental alteration associated with Moderna COVID-19 vaccine: a case report

Rizaldy Taslim Pinzon  1   2   3 , Fillia Kristyawati Haryono  4 , Nikolaus Erik Darmawan  4 , Mia Amelia Mutiara Salikim  4 , Vanessa Veronica  5
Affiliations
Case Reports

Acute dizziness and mental alteration associated with Moderna COVID-19 vaccine: a case report

Rizaldy Taslim Pinzon et al. BMC Neurol. .

Abstract

Background: Due to a rising number of COVID-19 cases, the Indonesian government implemented public health programs to lower the rate. Since January 2021, one of the government's primary policies has been the COVID-19 immunization program. Recently, the Moderna messenger ribonucleic acid (mRNA) vaccine is one of the COVID-19 vaccines used in Indonesia. Based on some research, Moderna has possible side effects throughout the body, including neurological symptoms.

Case presentation: We describe a 39-year-old female with uncontrolled hypertension who showed behavioral change, communication difficulty, social withdrawal, and a confused state within 7 days from getting her first dose of the Moderna vaccine. The patient had a history of febrile convulsion in childhood. An increase of neutrophil-to-lymphocyte ratio (16.9) and C-reactive protein level (31.75 mg/L) indicates ongoing inflammation. Head CT scan shows no abnormalities. She received ceftriaxone, citicoline, and methylprednisolone. The patient was discharged on the seventh day and completely recovered 1 week later. This study is the first case report of encephalopathy following the administration of the Moderna COVID-19 vaccine reported in Indonesia up to our knowledge.

Conclusion: Encephalopathy related to the Moderna COVID-19 vaccine should be acknowledged as an adverse effect of the Moderna COVID-19 vaccine.

Keywords: Acute dizziness; Encephalopathy; Mental alteration; Moderna; Vaccine.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Head CT-scan examination shows no abnormalities
See this image and copyright information in PMC

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