Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Oct;45(10):1255-1262.
doi: 10.1111/pace.14586. Epub 2022 Sep 8.

Pulsed electrical field in arrhythmia treatment: Current status and future directions

Affiliations
Review

Pulsed electrical field in arrhythmia treatment: Current status and future directions

Jie Qiu et al. Pacing Clin Electrophysiol. 2022 Oct.

Abstract

Pulsed electrical field (PEF) ablation is a promising novel ablation modality for the treatment of arrhythmia, especially for atrial fibrillation (AF). There have been several important advances in PEF ablation over the past several years, such as the parameters of PEF delivery and electrode Design. And the results in almost all clinical studies of PEF for AF ablation are optimistic, both in terms of effectiveness and safety. This article provides a brief overview of the mechanism and technical progress of PEF ablation in cardiac arrhythmia treatment, and discuss it's potential applications and the future development.

Keywords: atrial fibrillation; irreversible electroporation; pulsed electrical field.

PubMed Disclaimer

References

REFERENCES

    1. Reddy VY, Dukkipati SR, Neuzil P, et al. Pulsed field ablation of paroxysmal atrial fibrillation: 1-year outcomes of IMPULSE, PEFCAT, and PEFCAT II. JACC Clin Electrophysiol. 2021;7:614-627.
    1. Nakatani Y, Sridi-Cheniti S, Cheniti G, et al. Pulsed field ablation prevents chronic atrial fibrotic changes and restrictive mechanics after catheter ablation for atrial fibrillation. Europace. 2021;23:1767-1776.
    1. Füting A, Reinsch N, Howel D, et al. First experience with pulsed field ablation as routine treatment for paroxysmal atrial fibrillation. Europace. 2022;24:1084-1092.
    1. Gonzalez R, Scheinman M, Margaretten W, et al. Closed-chest electrode-catheter technique for His bundle ablation in dogs. Am J Physiol. 1981;241:H283-H287.
    1. Gallagher JJ, Svenson RH, Kasell JH, et al. Catheter technique for closed-chest ablation of the atrioventricular conduction system. N Engl J Med. 1982;306:194-200.

LinkOut - more resources