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. 1978 Aug;16(2):253-8.
doi: 10.1016/0090-6980(78)90027-8.

PGI2: a potential mediator of inflammation

PGI2: a potential mediator of inflammation

A W Ford-Hutchinson et al. Prostaglandins. 1978 Aug.

Abstract

PGI2, but not its metabolite 6oxoPGF1alpha, is equivalent in potency to PGE1 as a potentiator of carrageenan, histamine and bradykinin-induced rat paw oedemas. PGI2 must, therefore, be considered as a potential mediator of inflammatory processes.

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