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. 2022 Oct 1;84(10):1385-1390.
doi: 10.1292/jvms.22-0310. Epub 2022 Aug 26.

Local cerebral blood flow assessment using transcranial Doppler ultrasonography in a dog with brain infarction in the right middle cerebral artery territory

Kazuyoshi Sasaoka  1 , Hiroshi Ohta  2   3 , Tomohito Ishizuka  1 , Tatsuyuki Osuga  1   4 , Keitaro Morishita  1 , Noboru Sasaki  2 , Mitsuyoshi Takiguchi  2
Affiliations

Local cerebral blood flow assessment using transcranial Doppler ultrasonography in a dog with brain infarction in the right middle cerebral artery territory

Kazuyoshi Sasaoka et al. J Vet Med Sci. .

Abstract

A 12-year-old neutered male Chihuahua was diagnosed with acute brain infarction in the right middle cerebral artery (MCA) territory. Transcranial Doppler ultrasonography (TCD) was performed to assess the local cerebral blood flow at the time of diagnosis and after 4 and 31 hr. Initially, the right MCA retained blood flow but with a lower cerebral blood flow velocity (CBFV; 14.9 cm/sec) than the left MCA (27.9 cm/sec). The TCD vascular resistance variables were higher in the right than in the left MCA. An increase in the CBFV and a decrease in TCD vascular resistance variables were observed, consistent with improvements in neurological symptoms. TCD can be a non-invasive, and easy-to-use modality for bedside monitoring of cerebral edema and infarction.

Keywords: critical care; ischemic brain disease; neuroimaging; neurology; ultrasonography.

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Figures

Fig. 1.
Fig. 1.
Head computed tomography images with (A) transverse and (B) dorsal multiplanar reconstructions. The vascular territory of the right middle cerebral artery shows a low-attenuation lesion (arrowhead), suggesting brain infarction of the right middle cerebral artery territory.
Fig. 2.
Fig. 2.
(A) Transcranial Doppler ultrasonography images with color flow using a conventional ultrasound system. The ipsilateral middle cerebral artery is seen with the blood flowing (arrowhead) toward the probe placed on the temporal window. The arterial waveforms are obtained using pulsed Doppler on the visualized lesion. (B) Head computed tomography image of the same position as that of the ultrasonography image. (C, D) A three-dimensional schema of transcranial Doppler ultrasonography to the left middle cerebral artery created from computed tomography data.
Fig. 3.
Fig. 3.
Cerebral arterial Doppler waveforms using transcranial Doppler ultrasonography. The waveforms of the right middle cerebral artery (MCA, affected side), left middle cerebral artery (non-affected side), and basilar artery (A) at the time of diagnosis and (B) 4 and (C) 31 hr after treatment initiation. Diastolic blood flow on the affected side (arrow) is low compared with that on the opposite side. CBFV, cerebral blood flow velocity; PI, pulsatility index; RI, resistive index; Sm/Dm, ratio of systolic to diastolic mean velocity.
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