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Review
. 2022 Aug 10:9:931402.
doi: 10.3389/fvets.2022.931402. eCollection 2022.

Neurotrophic factors in the porcine ovary: Their effects on follicular growth, oocyte maturation, and developmental competence

Mirae Kim  1   2 , Sang-Hwan Hyun  1   2   3
Affiliations
Review

Neurotrophic factors in the porcine ovary: Their effects on follicular growth, oocyte maturation, and developmental competence

Mirae Kim et al. Front Vet Sci. .

Abstract

Pigs are cost-effective industrial animals because they produce a large number of offspring and have shorter rebreeding intervals compared with other animals, such as non-human primates. The reproductive physiology of pigs has been studied over the past several decades. However, there is not enough research on the effects of the neurotrophic factors on the ovarian physiology and development in pigs. As the ovary is a highly innervated organ, various neurotrophic factors during ovarian development can promote the growth of nerve fibers and improve the development of ovarian cells. Thus, investigating the role of neurotrophic factors on ovarian development, and the relationship between neurotrophic factors and porcine female reproduction is worth studying. In this review, we focused on the physiological roles of various neurotrophic factors in porcine ovaries and summarized the current status of the studies related to the relationship between neurotrophic factors and porcine ovarian development.

Keywords: female reproduction; folliculogenesis; neurotrophic factors; ovarian development; pig.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Schematic drawing of the neurotrophic factors involved in porcine ovarian and follicular development. Neurotrophic factors regulate porcine ovarian folliculogenesis, which involves follicle assembly, primordial follicle activation, follicular growth, steroidogenesis, oocyte maturation, ovulation, and corpus luteum formation. ND, no data.
See this image and copyright information in PMC

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