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Case Reports
. 2022 Aug 20:15:1711-1714.
doi: 10.2147/CCID.S376060. eCollection 2022.

Disseminated Kaposi Sarcoma

Jin-Yuan Ma  1 , Jia-Wei Liu  2
Affiliations
Case Reports

Disseminated Kaposi Sarcoma

Jin-Yuan Ma et al. Clin Cosmet Investig Dermatol. .

Abstract

AIDS-associated Kaposi sarcoma (KS) is the most common HIV-associated neoplasm. Disseminated Kaposi sarcoma became rare with the application of antiretroviral therapy. Oral AIDS-associated KS has prognostic relevance, indicating higher mortality than those with cutaneous lesions only. In this study, we reported a 40-year-old man presented with ulcerated violaceous plaques on his hard palate. Similar lesion can be observed on his left groin and anus, as well as on esophagus and gastric fundus under upper gastrointestinal endoscopy. Histological examination accorded with KS. After five cycles of doxorubicin, his oral, skin and esophagus lesions regressed considerably.

Keywords: AIDS; AIDS-associated Kaposi sarcoma; chemotherapy; disseminated Kaposi sarcoma; oral Kaposi sarcoma.

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Conflict of interest statement

All authors stated no potential conflicts of interest, including specific financial interests and relationships and affiliations relevant to the subject of the manuscript.

Figures

Figure 1
Figure 1
(A) purple ulcerated nodular plaque 2cm×2cm in diameter, together with another non-ulcerated nodule 1cm×1 cm in diameter on his left side of the hard palate. A small patch of violet plaque was visible behind the ulcerated plaque. (B) After five cycles of doxorubicin treatment, oral lesions had regressed considerably.
Figure 2
Figure 2
(A) Violaceous ulcerative plaques on esophagus and (B) violaceous plaques on gastric fundus under upper gastrointestinal endoscopy.
Figure 3
Figure 3
Histological examination revealed proliferating spindle cells with atypia, irregular vascular slits filled with blood cells which accorded with Kaposi sarcoma (hematoxylin and eosin, original magnification, ×400).
See this image and copyright information in PMC

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