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Case Reports
. 2022 Nov:83:104461.
doi: 10.1016/j.amsu.2022.104461. Epub 2022 Aug 20.

Sever erythema multiforme post-COVID-19 moderna vaccine: Case report and literature review

Abdalla Fadul  1 , El Mustafa Abdalla  1 , M Musa  1 , Abdulrhman Al-Mashdali  1 , Ahmed El Mudathir Osman  1 , Elabbass Abdelmahuod  1
Affiliations
Case Reports

Sever erythema multiforme post-COVID-19 moderna vaccine: Case report and literature review

Abdalla Fadul et al. Ann Med Surg (Lond). 2022 Nov.

Abstract

Introduction: Although the COVID-19 Vaccine usually causes a few non-serious side effects, serious ones such as Erythema multiforme recently has been linked to it.

Case presentation: Our patient presented with severe skin reaction one day post-Covid-19 Moderna vaccine diagnosed as erythema multiforme proven by skin biopsy that responded well to steroids.

Discussion: Erythema multiform major, an immune-mediated cutaneous reaction to infections or drugs involving the oral cavity, should be considered a possible adverse effect of numerous vaccinations, including SARSCoV2. Correct patient history gathering enables early detection and successful medical therapy with oral corticosteroids.Furthermore, the disease's rarity makes establishing a causative link difficult. However, because we are still learning about the innovative antiSARSCoV2 vaccines, it is crucial to be cautious of the potential cutaneous adverse responses.

Conclusion: Despite being rare, life-threatening adverse reactions can occur post-COVID-19 Vaccination.

Keywords: COVID-19; EM; Erythema multiform; Moderna; Vaccine.

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Conflict of interest statement

The authors have no competing of interest to declare.

Figures

Figure 1
Figure 1
Multiple dark erythematous, maculopapular lesions on the posterior trunk.
Figure 2
Figure 2
Many blisters and erosions on the lips, hard and soft palate, and buccal mucosa on both sides.
Figure 3
Figure 3
Multiple dark erythematous, maculopapular lesions on the lateral and posterior trunk, along with many blisters and erosions
See this image and copyright information in PMC

References

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