Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Aug 17:45:102193.
doi: 10.1016/j.eucr.2022.102193. eCollection 2022 Nov.

An extremely rare case of pseudomelanosis of the urinary bladder

Affiliations
Case Reports

An extremely rare case of pseudomelanosis of the urinary bladder

M Duijn et al. Urol Case Rep. .

Abstract

Pseudomelanosis (PM) is a rare, benign, condition that is characterized by deposition of melanin and/or melanin-like pigment in mucosal cells and macrophages and is best known as the entity pseudomelanosis coli. Pseudomelanosis primary of the urinary bladder has been reported only in a handful of cases worldwide. This article reports an extremely rare case of pseudomelanosis of the urinary bladder in a 79-year-old male with a history of macroscopic painless hematuria.

Keywords: Melanin; Melanin-like pigment; Melanosis; Pigmentation; Pseudomelanosis; Urinary bladder.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Cytology with candida and a pigmented urothelial cell.
Fig. 2
Fig. 2
A and B. Multiple black and brown pigmented lesions in the bladder during surgery. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 3
Fig. 3
Histology with abundant pigment in the upper layers of the urothelium and several pigment laden macrophages in the lamina propria.

References

    1. Rustagi T., Mansoor M.S., Gibson J.A., Kapadia C.R. Pseudomelanosis of stomach, duodenum, and jejunum. J Clin Gastroenterol. 2015;49(2):124–126. - PubMed
    1. Kevin P., Xuchen Z. Pseudomelanosis of the stomach and duodenum. J Clin Gastroenterol Treat. 2018;4(2) 4-057.
    1. Giusto D., Jakate S. Pseudomelanosis duodeni: associated with multiple clinical conditions and unpredictable iron stainability - a case series. Endoscopy. 2008;40(2):165–167. - PubMed
    1. Wieringa R.E., Blaauwgeers H.J., Van Andel G. Pseudomelanosis of the bladder: a case report. Acta Cytol. 2006;50:473–475. - PubMed
    1. Patel P., Gotto G., Kavanagh A., Bashir S Al, Bismar T.A., Trpkov K. Urinary bladder melanosis associated with urothelial dysplasia and invasive urothelial Carcinoma. Anal Quant Cytol Histol. 2013;35(5):294–300. - PubMed

Publication types

LinkOut - more resources