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Review
. 2022 Nov 1;28(6):537-542.
doi: 10.1097/MCP.0000000000000911. Epub 2022 Aug 30.

Adenotonsillectomy: the good, the bad and the unknown

Affiliations
Review

Adenotonsillectomy: the good, the bad and the unknown

Athanasios G Kaditis et al. Curr Opin Pulm Med. .

Abstract

Purpose of review: Adenotonsillar hypertrophy is the most common pathogenetic contributor to obstructive sleep apnea syndrome (OSAS) in childhood, and adenotonsillectomy is the standard initial treatment. Here, we summarize the most recent evidence on the efficacy and complications of adenotonsillectomy and explore knowledge gaps in clinical management.

Recent findings: Favorable adenotonsillectomy effects have been reported in children with very severe OSAS [apnea-hypopnea index (AHI) >20 episodes/h] and extremely severe OSAS (AHI >100 episodes/h), without postoperative mortality, need for endotracheal intubation, prolonged hospital stay or re-admission after hospital discharge. However, the risk of residual OSAS after adenotonsillectomy, which may reach 30-60%, has not been thoroughly established. Behavior, OSAS-related symptoms and quality of life improve postoperatively even in children with AHI 1-5 episodes/h. Natural history of enuresis resolution is accelerated postadenotonsillectomy and office-based systemic blood pressure is decreased in OSAS and hypertension. However, which children younger than 2 years should undergo adenotonsillectomy instead of adenoidectomy only to prevent recurrence of OSAS symptoms and revision surgery remains unclear. Adenotonsillectomy in children with Prader-Willi syndrome is frequently accompanied by postoperative residual OSAS while complications are not uncommon.

Summary: In the last 2 years, several studies have provided evidence supporting the efficacy and safety of adenotonsillectomy as treatment intervention for otherwise healthy children with OSAS.

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Conflict of interest statement

Conflict of Interest Disclosures: None of the authors have any conflicts of interest to disclose.

Conflicts of interest: None

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References

    1. Kaditis A, Alonso Alvarez ML, Boudewyns A et al. Obstructive sleep disordered breathing in 2- to 18-year-old children: diagnosis and management. Eur Respir J 2016; 47:69–94. - PubMed
    1. Marcus CL, Moore RH, Rosen CL et al. A randomized trial of adenotonsillectomy for childhood sleep apnea. N Engl J Med 2013; 368:2366–2376. - PMC - PubMed
    1. Bhattacharjee R, Kheirandish-Gozal L, Spruyt K et al. Adenotonsillectomy outcomes in treatment of obstructive sleep apnea in children: a multicenter retrospective study. Am J Respir Crit Care Med 2010; 182:676–683. - PubMed
    1. Van de Perck E, Van Hoorenbeeck K, Verhulst S et al. Effect of body weight on upper airway findings and treatment outcome in children with obstructive sleep apnea. Sleep Med 2021; 79:19–28. - PubMed
    2. The authors explored the effect of adiposity on patterns of upper airway obstruction using Drug-Induced Sleep Endoscopy (DISE) in otherwise healthy children with OSAS

    1. Uppalapati AV, Hubbell RD, Cheung AY et al. Severe Versus Very Severe Pediatric Obstructive Sleep Apnea Outcomes After Adenotonsillectomy. Laryngoscope 2021. - PubMed

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