Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Jun;29(3):230-3.

The induction of equine laminitis with an aqueous extract of the heartwood of black walnut (Juglans nigra)

P D Minnick, C M Brown, W E Braselton, G L Meerdink, M R Slanker
  • PMID: 3604042

The induction of equine laminitis with an aqueous extract of the heartwood of black walnut (Juglans nigra)

P D Minnick et al. Vet Hum Toxicol. 1987 Jun.

Abstract

An aqueous extract of the heartwood of black walnut (Juglans nigra) was given via stomach tube to 10 horses. Eight developed Obel grade 3 or 4 laminitis within 12 hr. Limb edema and mild sedation were the only other clinical signs observed. One horse was euthanized due to severe signs. The other 7 recovered within 6 days. Gas chromatography/mass spectrometry of aqueous extracts of heartwood, bark and nuts of black walnut identified juglone in the bark and nuts, but not in the heartwood. It was concluded that the aqueous extract of heartwood is laminogenic to horses, but the active ingredient is not juglone.

PubMed Disclaimer