Thin basement membrane lesion is not only a collagen IV nephropathy: do not underestimate "decorative" additions to collagens

Affiliations

¹ University of Cyprus Medical School, University of Cyprus, Nicosia, Cyprus; Center of Excellence in Biobanking and Biomedical Research, biobank.cy, Nicosia, Cyprus. Electronic address: deltas@ucy.ac.cy.

Comment

Constantinos Deltas. Kidney Int. 2022 Dec.

. 2022 Dec;102(6):1203-1205.

doi: 10.1016/j.kint.2022.08.014. Epub 2022 Aug 27.

¹ University of Cyprus Medical School, University of Cyprus, Nicosia, Cyprus; Center of Excellence in Biobanking and Biomedical Research, biobank.cy, Nicosia, Cyprus. Electronic address: deltas@ucy.ac.cy.

No abstract available

Keywords: Alport syndrome; collagen IV; post-translational modification; proly-3-hydroxylase; thin basement membrane nephropathy.

Comment on

Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy.
Aypek H, Krisp C, Lu S, Liu S, Kylies D, Kretz O, Wu G, Moritz M, Amann K, Benz K, Tong P, Hu ZM, Alsulaiman SM, Khan AO, Grohmann M, Wagner T, Müller-Deile J, Schlüter H, Puelles VG, Bergmann C, Huber TB, Grahammer F. Aypek H, et al. J Clin Invest. 2022 May 2;132(9):e147253. doi: 10.1172/JCI147253. J Clin Invest. 2022. PMID: 35499085 Free PMC article.