Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Sep-Oct;15(5):1218-1220.
doi: 10.1016/j.brs.2022.08.014. Epub 2022 Aug 28.

Accelerated tDCS improves corollary discharge deficit & prediction error signalling in schizophrenia: A case report

Swarna Buddha Nayok  1 , Anushree Bose  2 , Kiran Basawaraj Bagali  3 , Ketaki Maity  4 , Vanteemar S Sreeraj  3 , Venkataram Shivakumar  5 , Ganesan Venkatasubramanian  3
Affiliations
Case Reports

Accelerated tDCS improves corollary discharge deficit & prediction error signalling in schizophrenia: A case report

Swarna Buddha Nayok et al. Brain Stimul. 2022 Sep-Oct.
No abstract available

Keywords: Accelerated tDCS; Auditory hallucinations; Corollary discharge; Mismatch negativity; Schizophrenia.

PubMed Disclaimer

Conflict of interest statement

Declaration of competing interest None.

Figures

Figure 1
Figure 1
1(a) & 1(b) Correction of Corollary Discharge profile after AcctDCS sessions. The N100 component (–ve peak occurring between 60-150ms) should be attenuated in Talk condition but not in Listen condition indicating adequate corollary discharge. 1(c) Attenuation of correction of Corollary Discharge profile following extended acctDCS sessions. 1(d) & 1(e) rMMN profile correction following AcctDCS sessions. Roving MMN profile should be MMN33>MMN8>MMN3 in decreasing order of negativity as measured by N1 component (–ve peak occurring between 100-200ms). 1(f) Enhancement of rMMN amplitudes (more –ve peaks) and negligible change in rMMN profile (MMN33>MMN8>MMN3 pattern) following extended acctDCS sessions
See this image and copyright information in PMC

References

    1. Mondino M, Poulet E, Brunelin J. Moving to accelerated protocols of tDCS in schizophrenia: A case report. Brain Stimulation. 2021;14(4):822–824. - PubMed
    1. Bose A, et al. Effect of fronto-temporal transcranial direct current stimulation on corollary discharge in schizophrenia: A randomized, double-blind, sham-controlled mediation analysis study. Schizophr Res. 2019;204:411–412. - PubMed
    1. McCleery A, et al. Hallucinations, neuroplasticity, and prediction errors in schizophrenia. Scand J Psychol. 2018;59(1):41–48. - PMC - PubMed
    1. Brunoni AR, et al. A systematic review on reporting and assessment of adverse effects associated with transcranial direct current stimulation. Int J Neuropsychopharmacol. 2011;14(8):1133–45. - PubMed
    1. Ford JM, Roach BJ, Mathalon DH. Assessing corollary discharge in humans using noninvasive neurophysiological methods. Nature Protocols. 2010;5(6):1160–1168. - PMC - PubMed