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. 2022 Aug 30;21(1):81.
doi: 10.1186/s12944-022-01692-0.

The emerging role of skeletal muscle as a modulator of lipid profile the role of exercise and nutrition

Tzortzis Nomikos  1 , Spyridon Methenitis  2   3 , Demosthenes B Panagiotakos  4
Affiliations

The emerging role of skeletal muscle as a modulator of lipid profile the role of exercise and nutrition

Tzortzis Nomikos et al. Lipids Health Dis. .

Abstract

The present article aims to discuss the hypothesis that skeletal muscle per se but mostly its muscle fiber composition could be significant determinants of lipid metabolism and that certain exercise modalities may improve metabolic dyslipidemia by favorably affecting skeletal muscle mass, fiber composition and functionality. It discusses the mediating role of nutrition, highlights the lack of knowledge on mechanistic aspects of this relationship and proposes possible experimental directions in this field.

Keywords: Dyslipidemia; Exercise protocols; Intramuscular triglycerides; Lipid profile; Muscle fibers; Skeletal muscle.

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Conflict of interest statement

The authors declare that they have no competing interests.

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