[Serenity and objectivity in the face of severe childhood hepatitis: the diagnostic challenge]
- PMID: 36044771
- PMCID: PMC10395959
[Serenity and objectivity in the face of severe childhood hepatitis: the diagnostic challenge]
Abstract
The appearance of acute hepatitis of unknown aetiology in children has set off alarms in the World Health Organization and in member countries; identifying it and studying it lay out a diagnostic challenge for first-contact medical personnel and especially for pediatricians of Mexico, as well as for the coordination of care in health services. The international outlook and an analysis of the clinical manifestations are described, as well as key points for the identification and an observation of the samples that are requested for their study in Mexico.
La aparición de la hepatitis aguda infantil de etiología desconocida ha hecho que suenen las alarmas en la Organización Mundial de la Salud y en los países miembros; su identificación y estudio plantean un reto diagnóstico para el personal médico de primer contacto y en especial para los pediatras del país, así como para la coordinación de la atención en los servicios de salud. Se describe el panorama internacional y un análisis de las manifestaciones clínicas y los puntos clave para su identificación, así como una observación a las muestras que se solicitan para su estudio en México.
Keywords: Acute Hepatitis of Unknown Aetiology; Adenoviridae; SARS-CoV-2; Severe Acute Hepatitis.
© 2022 Revista Médica del Instituto Mexicano del Seguro Social.
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References
-
- UK Health Security Agency. Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 3. 2022. Disponible en: https://www.gov.uk/government/publications/acute-hepatitis-technical-bri... .
-
- Comité Nacional para la Vigilancia Epidemiológica. Aviso epidemiológico CONAVE/02/2022/Hepatitis grave de causa desconocida en niños. México: Comité Nacional para la Vigilancia Epidemiológica; 2022. Consultado: 19 de mayo de 2022. Disponible en: https://www.gob.mx/cms/uploads/attachment/file/727106/AE_Hepatitis_19052... .
-
- Curry MP, Chopra S. In: Mandell, Douglas, and Bennett’s principles and practice of infectious diseases. 7th. Mandell GL, Bennett JE, Dolin R, editors. USA: 2010. Acute Viral Hepatitis.
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