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. 2022 Aug 15:10:947097.
doi: 10.3389/fpubh.2022.947097. eCollection 2022.

Studies on irritable bowel syndrome associated with anxiety or depression in the last 20 years: A bibliometric analysis

Yuanfang Chen  1 , Baotao Lian  2 , Peize Li  1 , Simeng Yao  1 , Zhengkun Hou  3
Affiliations

Studies on irritable bowel syndrome associated with anxiety or depression in the last 20 years: A bibliometric analysis

Yuanfang Chen et al. Front Public Health. .

Abstract

Irritable bowel syndrome (IBS) associated with anxiety or depression is ubiquitous in clinical practice, and multiple related articles have been published. However, studies that utilize bibliometric analyses to address this topic are rare. In our study, we aimed to reveal research trends in IBS with anxiety or depression. Publications on IBS in relation to anxiety or depression in the last 20 years were obtained from the Web of Science Core Collection (WoSCC). CiteSpace software (5.8.R3) and GraphPad Prism 8 were used to perform bibliometric analysis of authors, countries, institutions, journals, keywords, and references involved in this topic. A total of 2,562 publications from 716 academic journals were included in this study. The majority of publications (n = 833, 32.51%) were from the USA, and the University of California, Los Angeles, contributed the most publications (n = 97, 3.79%). Active cooperations among countries and institutions were observed. Neurogastroenterology and Motility [impact factor (IF) 2020 = 3.598] published the most papers (170 publications, 6.64%), followed by Alimentary Pharmacology Therapeutics (IF 2020 = 8.171; 88 publications; 3.44%). The literatures related to IBS and anxiety or depression were primarily published in journals related to medicine/medical/clinical, neurology/sports/ophthalmology, and molecular/biology/immunology. Cryan JF and Drossman DA, with the largest number of articles (84 publications) and citations (917 citations), respectively, were considered as the most influential authors in this field. A total of 336 co-cited references were divided into 17 clusters, and #1 fecal microbiota transplantation contained most of the documents published in recent years. Moreover, the keyword "psychosocial factor" had the largest burst strength of 13.52, followed by the keyword "gut microbiota" with a burst strength of 11.71. This study shows the research performance of IBS related to anxiety or depression from 2002 to 2021 and helps researchers master the trend in this field, which should receive more attention.

Keywords: anxiety; bibliometrics; citespace; depression; irritable bowel syndrome.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Annual publications and growth forecast of IBS research related to anxiety or depression.
Figure 2
Figure 2
Collaboration network of countries in IBS research related to anxiety or depression.
Figure 3
Figure 3
Collaboration network of institutions in IBS research related to anxiety or depression.
Figure 4
Figure 4
The dual-map overlay of journals.
Figure 5
Figure 5
Authors' collaboration network of IBS research related to anxiety or depression.
Figure 6
Figure 6
Timeline view for references co-citation clusters.
Figure 7
Figure 7
Top 20 keywords with strongest strength of burst.
See this image and copyright information in PMC

References

    1. Black CJ, Craig O, Gracie DJ, Ford AC. Comparison of the Rome IV criteria with the Rome III criteria for the diagnosis of irritable bowel syndrome in secondary care. Gut. (2021) 70:1110–6. 10.1136/gutjnl-2020-322519 - DOI - PubMed
    1. Lovell R. M., Ford A. C. Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis. Clin Gastroenterol Hepatol. (2012) 10:712–21.e4. 10.1016/j.cgh.2012.02.029 - DOI - PubMed
    1. Frandemark A, Tornblom H, Jakobsson S, Simren M. Work productivity and activity impairment in irritable bowel syndrome (IBS): a multifaceted problem. Am J Gastroenterol. (2018) 113:1540–9. 10.1038/s41395-018-0262-x - DOI - PubMed
    1. Buono JL, Carson RT, Flores NM. Health-related quality of life, work productivity, and indirect costs among patients with irritable bowel syndrome with diarrhea. Health Qual Life Outcomes. (2017) 15:35. 10.1186/s12955-017-0611-2 - DOI - PMC - PubMed
    1. Singh P, Staller K, Barshop K, Dai E, Newman J, Yoon S, et al. . Patients with irritable bowel syndrome-diarrhea have lower disease-specific quality of life than irritable bowel syndrome-constipation. World J Gastroenterol. (2015) 21:8103–9. 10.3748/wjg.v21.i26.8103 - DOI - PMC - PubMed

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