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Review
. 2022 Jun 15:80:103881.
doi: 10.1016/j.amsu.2022.103881. eCollection 2022 Aug.

The effects of bariatric surgery on male and female fertility: A systematic review and meta-analysis

Affiliations
Review

The effects of bariatric surgery on male and female fertility: A systematic review and meta-analysis

Abdullah A Al Qurashi et al. Ann Med Surg (Lond). .

Abstract

•Currently natural lifestyle modification is recommended over bariatric surgery in the management of infertility in obese men and women, despite natural weight loss often being an ineffective method to both lose and maintain weight loss in these individuals.•Through this meta-analysis and systematic review, we provide evidence that bariatric surgery effectively improves fertility outcomes for men and women by measurements of hormone levels and improvements in sexual function index scores.•This study demonstrates the importance and even cruciality of bariatric surgery in obese men and women who struggle with reproductive health, especially when finding it difficult to lose and maintain weight. It also proves that it is vital to continue to create and expand our knowledge with evidence-based medicine to help this cohort of patients.

Keywords: Bariatric surgery; Obesity; Semen analysis; Sex hormones; Sexual function.

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Conflict of interest statement

None of the authors have any conflicts of interest in this study.

Figures

Fig. 1
Fig. 1
PRISMA flow diagram outlining literature search process.
Fig. 2
Fig. 2
This Forrest plot summarizes the results of our meta-analysis demonstrating the effects of bariatric surgery on outcomes of fertility in females.
Fig. 3
Fig. 3
This Forrest plot summarizes the results of our meta-analysis demonstrating the effects of bariatric surgery on outcomes of fertility in males.

References

    1. Obesity and overweight. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
    1. Best D., Bhattacharya S. Obesity and fertility. Horm. Mol. Biol. Clin. Invest. 2015;24(1):5–10. doi: 10.1515/hmbci-2015-0023. - DOI - PubMed
    1. Talmor A., Dunphy B. Female obesity and infertility. Best Pract. Res. Clin. Obstet. Gynaecol. 2015;29(4):498–506. doi: 10.1016/j.bpobgyn.2014.10.014. - DOI - PubMed
    1. Craig J.R., Jenkins T.G., Carrell D.T., Hotaling J.M. Obesity, male infertility, and the sperm epigenome. Fertil. Steril. 2017;107(4):848–859. doi: 10.1016/j.fertnstert.2017.02.115. - DOI - PubMed
    1. Chang C., Chang S., Poles J., Popov V. The impact of bariatric surgery compared to metformin therapy on pregnancy outcomes in patients with polycystic ovarian syndrome: a systematic review and meta-analysis. J. Gastrointest. Surg. Off. J. Soc. .Surg. Aliment Tract. 2021;25(2):378–386. doi: 10.1007/s11605-020-04900-3. - DOI - PubMed