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Case Reports
. 2022 Jul 31:80:104216.
doi: 10.1016/j.amsu.2022.104216. eCollection 2022 Aug.

Uncommon presentation of isolated laryngeal sarcoidosis in a young man

Affiliations
Case Reports

Uncommon presentation of isolated laryngeal sarcoidosis in a young man

Bayan O Besharah et al. Ann Med Surg (Lond). .

Abstract

•Sarcoidosis is a chronic multisystemic granulomatous disease with unknown etiology.•Sarcoidosis affects the head and neck region in only 10%-15% of cases.•Larynx with turban-like thickening should raise high suspicions of laryngeal sarcoidosis.•Sarcoidosis is diagnosed after laboratory, endoscopic, and histopathology findings exclude other differentials.•Isolated laryngeal sarcoidosis is rare, making early diagnosis challenging and rising misdiagnosis.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
Flexible laryngoscopic view shows polypoidal changes over the epiglottis, arytenoids, and aryepiglottic folds with moderate pale-pink mucosal edema. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 2
Fig. 2
Flexible laryngoscopic view: (A) After three months postoperative shows significant improvement of the mucosa of epiglottis, arytenoids, and aryepiglottic folds. (B) After 24 months of starting oral steroids, mucosal edema greatly improved.

References

    1. Agha R.A., Franchi T., Sohrabi C., Mathew G., for the SCARE Group The SCARE 2020 guideline: updating consensus surgical CAse REport (SCARE) guidelines. Int. J. Surg. 2020;84:226–230. - PubMed
    1. Leedman S.R., Hendriks T., Leahy T.W., Hall D. Supraglottic laryngeal sarcoidosis masquerading as supraglottitis. BMJ Case Rep. CP. 2020;13(1) - PMC - PubMed
    1. Kelleher K.J., Russell J., Killeen O.G., Leahy T.R. Treatment-recalcitrant laryngeal sarcoidosis responsive to sirolimus. BMJ Case Rep. CP. 2020;13(8) - PMC - PubMed
    1. Hong S.A., Bell J.R. Progressive upper airway obstruction and dysphagia in a child with supraglottic edema. JAMA Otolaryngol. Head . Neck Surg. 2013;146(11):1073–1074. - PubMed
    1. Edriss H., Kelley J.S., Demke J., Nugent K. Sinonasal and laryngeal sarcoidosis—an uncommon presentation and management challenge. Am. J. Med. Sci. 2019;357(2):93–102. - PubMed

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