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. 2022 Jan-Mar;23(1):61-66.
doi: 10.18502/jri.v23i1.8454.

Assisted Reproductive Technologies in the Republic of Kazakhstan: A 6-Year Trend Analysis from Efficacy to Availability

Vyacheslav Lokshin  1 , Meruyert Omar  2 , Sholpan Karibaeva  1
Affiliations

Assisted Reproductive Technologies in the Republic of Kazakhstan: A 6-Year Trend Analysis from Efficacy to Availability

Vyacheslav Lokshin et al. J Reprod Infertil. 2022 Jan-Mar.

Abstract

Background: The first child after in vitro fertilization (IVF) in the country was born in 1996. However, registering and recording data on assisted reproductive technologies (ARTs) in Kazakhstan is not mandatory. The purpose of the current study was to assess the treatment outcomes, availability, regulations, and ART cycles trends between 2011 and 2016.

Methods: Cycle-based data were collected from voluntarily participating ART centers and then descriptive analysis was performed. The study included 10470 ART cycles using different ART methods during 2011-2016. The availability rate of ART in the country was calculated by dividing the number of treatment cycles per million of the population.

Results: The availability of ART per million inhabitants increased by 53.6%, from 236.9/million in 2011, to 364.0/million in 2016. In IVF cycles, clinical pregnancy rates (PRs) per aspiration remained stable, on average 37.1%. After ICSI, the average PR was 42.5%. In frozen embryo replacement cycles, there was an increase in the PR per transfer from 37.0% in 2011, to 42.5% in 2016, on average 39.2%.

Conclusion: Assisted reproductive technologies are developing rapidly in Kazakhstan; therefore, ART monitoring should be improved and become mandatory. Although the data is not yet representative, the most compelling evidence points to low access to ART. Since the use of ART in Central Asian countries is infrequent in comparison to European countries, there is a need to combine IVF data across different nations. This will allow for a deeper assessment of the scientific evidence and reduction of infertility burden through joint efforts.

Keywords: Assisted reproductive technologies; Availability; IVF; Infertility.

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Conflict of interest statement

Conflict of Interest Authors declare that there is no conflict of interest.

Figures

Figure 1.
Figure 1.
Map of Kazakhstan with the number of clinics
Figure 2.
Figure 2.
The number of ART cycles per year in the RK
Figure 3.
Figure 3.
The ratio of IVF versus ICSI between 2011–2016
See this image and copyright information in PMC

References

    1. Lokshin V, Irina K. Personified approach to genetic screening of infertility couples in art programs. Medicine. 2018; 1(317):37–41.
    1. Lokshin V. Dhusubalieva. Assisted reproductive technologies in the Republic of Kazakhstan according to the 2011 register. Reprod uktivnaya Med. 2013; 275:5–10.
    1. Nygren KG, Sullivan E, Zegers-Hochschild F, Mansour R, Ishihara O, Adamson GD, et al. International committee for monitoring assisted Reproductive technology (ICMART) world report: assisted reproductive technology 2003. Fertil Steril. 2011;95(7): 2209–2222.e1-e17. - PubMed
    1. Lokshin V, Dhusubalieva T. Clinical Practice in Reproductive Medicine. 1st ed. Almaty: MedMedia. 2015. 566 p.
    1. Agadjanian V, Dommaraju P, Nedoluzhko L. Economic fortunes, ethnic divides, and marriage and fertility in Central Asia: Kazakhstan and Kyrgyzstan compared. J Popul Res. 2013;30(3):197–211.

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