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. 2022 Jan-Mar;17(1):10-17.
doi: 10.18502/ijpa.v17i1.9011.

Seroprevalence of Human Toxocariasis in Children (5-15-Year-Old) Using ELISA Method in Ardabil District, North-West of Iran

Zahra Heidari  1 , Zahra Alizadeh  2 , Hamid Afzoun Khiyavi  3 , Soheila Molaei  4 , Abdollah Mahdavi  5 , Behnam Mohammadi-Ghalehbin  1
Affiliations

Seroprevalence of Human Toxocariasis in Children (5-15-Year-Old) Using ELISA Method in Ardabil District, North-West of Iran

Zahra Heidari et al. Iran J Parasitol. 2022 Jan-Mar.

Abstract

Background: Toxocariasis is a worldwide-distributed helminth parasitic infection. This study aimed to evaluate the seroprevalence of human toxocariasis in children living in Ardabil Province, North-West of Iran.

Methods: A seroepidemiological study to evaluate human toxocariasis among urban and rural populations of Ardabil County, North-West of Iran using ELISA test was carried out from 2019 to 2020. The study population was 472 children (185 females and 287 males) aged between 5 and 15 yr old. Immunoglobulin G antibodies against Toxocara spp. were analyzed by ELISA test.

Results: Of the 472 collected serum samples, 66 (14.0%) were positive for antibodies against human toxocariasis. The highest prevalence of infection was observed in children with age groups of 5-6 years. Data demonstrate higher seroprevalence among males (15.3%) than females (11.8%). Rural areas prevalence was significantly higher (24.4%) than the urban area (8.65%). The rate of the diseases was 22.8% in children having history of contact with dog.

Conclusion: Toxocariasis is prevalent in the children of Ardabil region. The present study can increase the awareness of the population about the risk of zoonotic diseases as well as the anthelmintic treatment of dogs by veterinarians and, more importantly, the control of stray dogs.

Keywords: Human toxocariasis; Iran; Seroepidemiology.

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Conflict of interest statement

Conflict of interest The authors declare that there is no conflict of interest.

Figures

Fig. 1:
Fig. 1:
Left: map of Iran and Ardabil Province, Right: map of districts in Ardabil Province, from where the serum samples were collected
Fig. 2:
Fig. 2:
Analysis of sera from subjects and normal controls by IgG-ELISA
Fig. 3:
Fig. 3:
Distribution of positive cases of toxocariasis using ELISA according to age group (yr) in Ardabil Province, North-West of Iran
See this image and copyright information in PMC

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