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. 2022 Oct;41(10):1335-1347.
doi: 10.1016/j.healun.2022.08.007. Epub 2022 Aug 20.

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-ninth adult lung transplantation report-2022; focus on lung transplant recipients with chronic obstructive pulmonary disease

Michael Perch  1 , Don Hayes Jr  1 , Wida S Cherikh  1 , Andreas Zuckermann  1 , Michael O Harhay  1 , Eileen Hsich  1 , Luciano Potena  1 , Aparna Sadavarte  1 , Kelsi Lindblad  1 , Tajinder P Singh  1 , Josef Stehlik  2 ; International Society for Heart and Lung Transplantation  1
Affiliations

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-ninth adult lung transplantation report-2022; focus on lung transplant recipients with chronic obstructive pulmonary disease

Michael Perch et al. J Heart Lung Transplant. 2022 Oct.
No abstract available

Keywords: COPD; lung transplantation; morbidity; post-transplant survival; recipient characteristics; registry.

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Figures

Figure 1
Figure 1
Diagnosis distribution by location and era (transplants: January 1992-June 2018).
Figure 2
Figure 2
Median recipient A) age and B) body mass index (BMI) by location (COPD transplants: January 1992-June 2018).
Figure 3
Figure 3
Relative incidence of leading causes of death (COPD transplant deaths: January 2010-June 2018).
Figure 4
Figure 4
Cumulative incidence of leading causes of death (COPD transplants: January 2010-June 2017).
Figure 5
Figure 5
Kaplan-Meier survival within 12 months by era (COPD transplants: January 2000-June 2017).
Figure 6
Figure 6
Kaplan-Meier survival within 12 months by diagnosis (transplants: January 2000-June 2017).
Figure 7
Figure 7
Kaplan-Meier survival within 12 months by age and procedure type (COPD transplants: January 2000-June 2017).
Figure 8
Figure 8
Kaplan-Meier survival within 5 years conditional on survival to 1 year by recipient age (COPD transplants: January 1996-June 2013).
Figure 9
Figure 9
Kaplan-Meier survival within 5 years conditional on survival to 1 year by diagnosis (transplants: January 1996-June 2013).
Figure 10
Figure 10
Kaplan-Meier survival within 5 years conditional on survival to 1 year by recipient age and procedure type (COPD transplants: January 2000-June 2017).
Figure 11
Figure 11
Freedom from BOS/CLAD conditional on survival to discharge by procedure type (COPD transplants: January 1996-June 2013).
Figure 12
Figure 12
Freedom from new onset of A) lung cancer and B) non-lung cancer, conditional on survival to 1 year by procedure type (COPD transplants: January 1996-June 2017).
Figure 13
Figure 13
Multivariable hazard ratio plot for 1-year mortality with 95% confidence limits, by recipient age (COPD transplants: January 2000-June 2017; N = 15,643).
Figure 14
Figure 14
Multivariable hazard ratio plot for 5-year mortality conditional on survival to 1 year with 95% confidence limits, by A) recipient age and B) recipient body mass index (BMI) (COPD transplants: January 1996-June 2013; N = 11,683).
Figure 15
Figure 15
Statistically significant risk factors for BOS/CLAD within 5 years conditional on survival to discharge with 95% confidence limits (COPD transplants: January 1996-June 2013; N = 6,181).
Figure 16
Figure 16
Statistically significant risk factors for BOS/CLAD within 5 years conditional on survival to discharge with 95% confidence limits, by PRA (COPD transplants: January 1996-June 2013; N = 6,181).
See this image and copyright information in PMC

References

    1. Stehlik J, Christie JD, Goldstein DR, et al. The evolution of the ISHLT transplant registry. Preparing for the future. J Heart Lung Transplant 2021;40:1670–81. - PubMed
    1. Yusen RD, Christie JD, Edwards LB, et al. The Registry of the International Society for Heart and Lung Transplantation: Thirtieth Adult Lung and Heart-Lung Transplant Report–2013; focus theme: age. J Heart Lung Transplant 2013;32:965–78. - PubMed
    1. Lund LH, Edwards LB, Kucheryavaya AY, et al. The registry of the International Society for Heart and Lung Transplantation: thirty-first official adult heart transplant report–2014; focus theme: retransplantation. J Heart Lung Transplant 2014;33:996–1008. - PubMed
    1. Yusen RD, Edwards LB, Kucheryavaya AY, et al. The registry of the International Society for Heart and Lung Transplantation: Thirty-second Official Adult Lung and Heart-Lung Transplantation Report–2015; focus theme: early graft failure. J Heart Lung Transplant 2015;34:1264–77. - PubMed
    1. Yusen RD, Edwards LB, Dipchand AI, et al. The registry of the International Society for Heart and Lung Transplantation: Thirty-third Adult Lung and Heart-Lung Transplant Report-2016; focus theme: primary diagnostic indications for transplant. J Heart Lung Transplant 2016;35:1170–84. - PubMed