Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Feb;50(2):131-133.
doi: 10.1111/cup.14320. Epub 2022 Sep 26.

Pleomorphic acquired digital fibrokeratoma: A novel clinicopathologic entity

Affiliations
Case Reports

Pleomorphic acquired digital fibrokeratoma: A novel clinicopathologic entity

Leo L Wang et al. J Cutan Pathol. 2023 Feb.

Abstract

A 26-year-old male presented with a 2-year history of a hyperkeratotic growth from the left index finger. Histopathology was consistent with an acquired digital fibrokeratoma with changes of a pleomorphic fibroma. Lesional cells were negative for CD34, Rb, and p53, and were positive for FXIIIa. We introduce the pleomorphic acquired digital fibrokeratoma as a novel clinicopathologic entity.

Keywords: acquired digital fibrokeratoma; pleomorphic fibroma.

PubMed Disclaimer

References

REFERENCES

    1. Bart RS, Andrade R, Kopf AW, et al. Acquired digital fibrokeratomas. Arch Dermatol. 1968;97:120-128.
    1. Nemeth AJ, Penneys NS. Factor XIIIa is expressed by fibroblasts in fibrovascular tumors. J Cutan Pathol. 1989;16(5):266-271. doi:10.1111/J.1600-0560.1989.TB00050.X
    1. Shih S, Khachemoune A. Acquired digital fibrokeratoma: review of its clinical and dermoscopic features and differential diagnosis. Int J Dermatol. 2019;58(2):151-158. doi:10.1111/IJD.14046
    1. Kamino H, Lee JY-Y, Berke A. Pleomorphic fibroma of the skin: a benign neoplasm with cytologic atypia: a clinicopathologic study of eight cases. Am J Surg Pathol. 1989;13(2):107-113.
    1. Rudolph P, Schubert C, Zelger BG, Zeiger B, Parwaresch R. Differential expression of CD34 and Ki-M1p in pleomorphic fibroma and dermatofibroma with monster cells. Am J Dermatopathol. 1999;21(5):414-419. doi:10.1097/00000372-199910000-00002

Publication types