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. 2022 Aug 26:13:289-295.
doi: 10.2147/PHMT.S371914. eCollection 2022.

Main Clinical and Laboratory Features of Children with Bacterial Meningitis: Experience from a Tertiary Paediatric Centre in Central Vietnam

Chau Duc Nguyen-Huu  1 , Son Bui-Binh-Bao  1 , Kiem Hao Tran  2 , Van Tuan Mai  3 , Diem Chi Nguyen-Thi  2 , Hanh Chan Tran-Thi  2 , Anh Nguyen-Duy-Nam  1 , Phuc To  1 , Van Anh Ton-Nu  1
Affiliations

Main Clinical and Laboratory Features of Children with Bacterial Meningitis: Experience from a Tertiary Paediatric Centre in Central Vietnam

Chau Duc Nguyen-Huu et al. Pediatric Health Med Ther. .

Abstract

Objective: Our study aimed to summarize symptoms and laboratory findings of bacterial meningitis at a Vietnam tertiary care hospital.

Methods: We performed a retrospective study and enrolled 33 children diagnosed with bacterial meningitis admitted at the Pediatric Center, Hue Central Hospital, between January 2019 and July 2021.

Results: Only 24.2% (8 out of 33) cases can determine etiology of bacterial meningitis. Streptococcus pneumonia was the most common pathogen. The mortality in this study was 12.1%. The most commn symptoms were fever (93.9%) and vomiting (60.6%). Loss of consciousness and poor appetite were predominant among patients who died (75%); seizures and local paralysis accounted for a half. For cerebrospinal fluid (CSF), the cloudy or turbid color was the most common in bacterial meningitis (54.5%), CSF leucocytes in a half of patients were greater than 500 cells/mm3 (48.5%). CSF white blood cells count was higher among children who died.

Conclusion: Streptococcus pneumonia was the most common pathogen. Fever, vomiting, loss of consciousness, local paralysis, and increased leucocytes, neutrophils of CSF were more common in severe cases.

Keywords: S. pneumonia; Vietnam; bacterial meningitis; cerebrospinal fluid.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

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