The Roles of Unrecognized Mpox Cases, Contact Isolation and Vaccination in Determining Epidemic Size in Belgium: A Modeling Study
- PMID: 36052546
- DOI: 10.1093/cid/ciac723
The Roles of Unrecognized Mpox Cases, Contact Isolation and Vaccination in Determining Epidemic Size in Belgium: A Modeling Study
Abstract
We used a network model to simulate a mpox epidemic among men who have sex with men. Our findings suggest that unrecognized infections have an important impact on the epidemic, and that vaccination of individuals at highest risk of infection reduces epidemic size more than post-exposure vaccination of sexual partners.
Keywords: MSM; mathematical model; mpox; outbreak; vaccination.
© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Conflict of interest statement
Potential conflicts of interest. N. H. reports grants or contracts from Scientific chair in evidence-based vaccinology sponsored by a gift from Pfizer (2009–2019) and GSK (2016) (paid University of Antwerp; no personal remuneration), and Specific research grants sponsored by MSD, Janssen Vaccines & Prevention, GSK - Glaxo SmithKline outside the submitted work (Payments made to the universities of Antwerp and Hasselt; no personal remuneration); and consulting fees from Janssen Global Services (Participation in advisory board related to RSV disease transmission modelling; payments made to Hasselt University; no personal remuneration). All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.
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