. 2022 Sep 2;11(9):e21878.

doi: 10.2196/21878.

Design and Rationale of the National Observational Multicentric Tunisian Registry of Hypertension: Protocol for Evaluating Hypertensive Patient Care in Clinical Practice

Leila Abid¹, Rania Hammami^#^{1

2}, Salem Abdesselem¹, Selim Boudiche³, Ben Slima Hédi⁴, Khaled Sayahi⁵, Amine Bahloul², Ikram Chamtouri⁶, Salma Charfeddine², Lamia Rais⁷, Meriem Drissa⁸, Badreddine Ben Kaab⁷, Hassen Ibn Hadj Amor⁹, Lilia Ben Fatma⁷, Riadh Garbaa¹, Sabrine Boukhris⁸, Allouche Emna¹⁰, Manel Ben Halima³, Nesrine Amdouni⁶, Shayma Ghorbel¹¹, Sabrine Soudani⁸, Imen Khaled¹², Syrine Triki², Feten Bouazizi¹², Imen Jemai¹³, Ouday Abdeljalil⁶, Yemna Ammar¹², Amani Farah⁶, Adnen Neji¹⁴, Zeineb Oumaya¹⁰, Sana Seghaier¹⁵, Samir Mokrani¹⁶, Hamza Thawaba¹, Hela Sarray², Khalil Ouaghlani¹⁰, Houssem Thabet¹⁷, Zeineb Mnif¹⁸, Boujelben Masmoudi Fatma¹, Mohamed Sghaier¹, Roueida Khalifa⁶, Sami Fourati¹, Yassmine Kammoun², Syrine Abid¹, Chiheb Hamza¹, Syrine Ben Jeddou⁸, Lassaad Sabbah¹⁹, Rim Lakhdhar¹, Najla Dammak²⁰, Tarak Sellami¹, Basma Herbegue¹, Alia Koubaa²¹, Faten Triki², Tarek Ellouze², Aicha Hmoudi²², Ikhlas Ben Ameur¹, Mohamed Mongi Boukhchina²³, Neila Abid¹⁹, Wejdene Ouechtati¹⁰, Nizar Nasrallah²⁴, Yousra Houidi²⁵, Fathia Mghaieth Zghal³, Ghodhbane Elhem²², Mounira Chayeb²⁵, Chenik Sarra²⁶, Samira Kaabachi⁸, Nizar Saadaoui¹, Ines Ben Ameur¹, Moufida Affes¹⁹, Sana Ouali³, Mouna Chaker², Hela Naana¹, Dghim Meriem²⁶, Mourad Jarrar¹, Jihen Mnif¹, Ahmed Turki², Ihsen Zairi²⁷, Jamel Langar¹, Safa Dardouri¹⁷, Imen Hachaichi²⁸, Rafik Chettaoui¹, Wajih Smat¹, Amel Chakroun²⁹, Khadija Mzoughi²⁷, Rachid Mechmeche¹, Afef Ben Halima³⁰, Sahar Ben Kahla Koubaa³¹, Slim Chtourou¹, Maalej Mohamed Abdelkader¹, Mohsen Ayari³², Moufid Hadrich¹, Tlili Rami³³, Fares Azaiez³³, Imen Bouhlel¹⁷, Samir Sahnoun¹⁹, Habib Jerbi³⁴, Ben Mrad Imtinene²⁷, Leila Riahi²⁶, Mohamed Sahnoun¹, Abdelhamid Ben Jemaa², Amal Ben Salem¹⁰, Bassem Rekik¹⁰, Maroua Ben Doudou²⁷, Mohamed Rachid Boujnah¹, Anissa Joulak¹, Abid Omar², Rabie Razgallah³⁵, Milouchi Sami¹¹, Elyes Neffati³⁶, Habib Gamra³⁷, Soraya Ben Youssef³⁸, Wissem Sdiri³⁹, Nejeh Ben Halima⁴⁰, Youssef Ben Ameur³³, Salem Kachboura³⁰, Sondes Kraiem²⁷, Wafa Fehri²⁶, Lilia Zakhama³⁸, Leila Bezdah¹⁰, Mourali Mohamed Sami³, Habiba Drissa⁸, Mohamed Faouzi Maatouk⁶, Samir Kammoun², Faouzi Addad^{1

30}

Affiliations

¹ Tunisian Society of Cardiology and Cardiovascular Surgery, Tunis, Tunisia.
² Cardiology Department, Hedi Chaker-Sfax University Hospital, Faculty of Medecine of Sfax, University of Sfax, Sfax, Tunisia.
³ Cardiology Department, La Rabta 1 (Pr Mourali) University Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
⁴ Cardiology Department, Hospital of Menzel Bourguiba, Bizerte, Tunisia.
⁵ Cardiology Department, ElKef Hospital, Elkef, Tunisia.
⁶ Cardiology Department B, Fattouma Bourguiba University Hospital, Faculty of Medecine of Monastir, University of Monastir, Monastir, Tunisia.
⁷ Nephrology Department, La Rabta University Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
⁸ Cardiology Department, La Rabta 2 (Pr Drissa) University Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
⁹ Cardiology Department, Tahar Sfar Hospital, Mahdia, Tunisia.
¹⁰ Cardiology Department, Charles Nicole University Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
¹¹ Cardiology Department, Habib Bourguiba Hospital, Medenine, Tunisia.
¹² Basic Health Centers, Medenine, Tunisia.
¹³ Habib Bourguiba Hospital, Medenine, Tunisia.
¹⁴ Hospital of Tozeur, Tozeur, Tunisia.
¹⁵ Private clinic, Tunis, Tunisia.
¹⁶ Hospital of Mateur, Bizerte, Tunisia.
¹⁷ Cardiology Department, Farhat Hached Hospital, Faculty of Medecine of Sousse, University of Sousse, Sousse, Tunisia.
¹⁸ National Social Security Fund, Sfax, Tunisia.
¹⁹ Private clinic, Sfax, Tunisia.
²⁰ Nephrology Department, Hedi Chaker-Sfax University Hospital, Faculty of Medecine of Sfax, University of Sfax, Sfax, Tunisia.
²¹ Basic Health Centers, Ben Arous, Tunisia.
²² Basic Health Centers, Tataouine, Tunisia.
²³ Private clinic, Gabes, Tunisia.
²⁴ Private clinic, Ariana, Tunisia.
²⁵ Basic Health Centers, Tunis, Tunisia.
²⁶ Cardiology Department, The Main Military Instruction Hospital of Tunis, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
²⁷ Cardiology Department, Habib Thameur Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
²⁸ Basic Health Centers, Gabes, Tunisia.
²⁹ Hospital of Habib Bougatfa, Bizerte, Tunisia.
³⁰ Cardiology Department, Abderrahmen Mami-Ariana Hospital, Faculty of Medecine of Tunis, University of Tunis, Ariana, Tunisia.
³¹ Cardiology Department, Mahres Hospital, Faculty of Medecine of Sfax, University of Sfax, Sfax, Tunisia.
³² Private clinic, Nabeul, Tunisia.
³³ Cardiology Department, Mongi Slim Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
³⁴ Private clinic, Sousse, Tunisia.
³⁵ Dacima, Tunis, Tunisia.
³⁶ Cardiology Department, University Hospital Sahloul, Faculty of Medecine of Sousse, Sousse, Tunisia.
³⁷ Cardiology Department A, Fattouma Bourguiba University Hospital, Faculty of Medecine of Monastir, University of Monastir, Monastir, Tunisia.
³⁸ Cardiology Department, Internal Security Forces Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
³⁹ Cardiology Department, Bougatfa Hospital, Bizerte, Tunisia.
⁴⁰ Cardiology Department, Ibn El Jazzar Hospital, Kairouan, Tunisia.

^# Contributed equally.

PMID: 36053572
PMCID: PMC9482066
DOI: 10.2196/21878

Design and Rationale of the National Observational Multicentric Tunisian Registry of Hypertension: Protocol for Evaluating Hypertensive Patient Care in Clinical Practice

Leila Abid et al. JMIR Res Protoc. 2022.

. 2022 Sep 2;11(9):e21878.

doi: 10.2196/21878.

Authors

Affiliations

¹ Tunisian Society of Cardiology and Cardiovascular Surgery, Tunis, Tunisia.
² Cardiology Department, Hedi Chaker-Sfax University Hospital, Faculty of Medecine of Sfax, University of Sfax, Sfax, Tunisia.
³ Cardiology Department, La Rabta 1 (Pr Mourali) University Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
⁴ Cardiology Department, Hospital of Menzel Bourguiba, Bizerte, Tunisia.
⁵ Cardiology Department, ElKef Hospital, Elkef, Tunisia.
⁶ Cardiology Department B, Fattouma Bourguiba University Hospital, Faculty of Medecine of Monastir, University of Monastir, Monastir, Tunisia.
⁷ Nephrology Department, La Rabta University Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
⁸ Cardiology Department, La Rabta 2 (Pr Drissa) University Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
⁹ Cardiology Department, Tahar Sfar Hospital, Mahdia, Tunisia.
¹⁰ Cardiology Department, Charles Nicole University Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
¹¹ Cardiology Department, Habib Bourguiba Hospital, Medenine, Tunisia.
¹² Basic Health Centers, Medenine, Tunisia.
¹³ Habib Bourguiba Hospital, Medenine, Tunisia.
¹⁴ Hospital of Tozeur, Tozeur, Tunisia.
¹⁵ Private clinic, Tunis, Tunisia.
¹⁶ Hospital of Mateur, Bizerte, Tunisia.
¹⁷ Cardiology Department, Farhat Hached Hospital, Faculty of Medecine of Sousse, University of Sousse, Sousse, Tunisia.
¹⁸ National Social Security Fund, Sfax, Tunisia.
¹⁹ Private clinic, Sfax, Tunisia.
²⁰ Nephrology Department, Hedi Chaker-Sfax University Hospital, Faculty of Medecine of Sfax, University of Sfax, Sfax, Tunisia.
²¹ Basic Health Centers, Ben Arous, Tunisia.
²² Basic Health Centers, Tataouine, Tunisia.
²³ Private clinic, Gabes, Tunisia.
²⁴ Private clinic, Ariana, Tunisia.
²⁵ Basic Health Centers, Tunis, Tunisia.
²⁶ Cardiology Department, The Main Military Instruction Hospital of Tunis, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
²⁷ Cardiology Department, Habib Thameur Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
²⁸ Basic Health Centers, Gabes, Tunisia.
²⁹ Hospital of Habib Bougatfa, Bizerte, Tunisia.
³⁰ Cardiology Department, Abderrahmen Mami-Ariana Hospital, Faculty of Medecine of Tunis, University of Tunis, Ariana, Tunisia.
³¹ Cardiology Department, Mahres Hospital, Faculty of Medecine of Sfax, University of Sfax, Sfax, Tunisia.
³² Private clinic, Nabeul, Tunisia.
³³ Cardiology Department, Mongi Slim Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
³⁴ Private clinic, Sousse, Tunisia.
³⁵ Dacima, Tunis, Tunisia.
³⁶ Cardiology Department, University Hospital Sahloul, Faculty of Medecine of Sousse, Sousse, Tunisia.
³⁷ Cardiology Department A, Fattouma Bourguiba University Hospital, Faculty of Medecine of Monastir, University of Monastir, Monastir, Tunisia.
³⁸ Cardiology Department, Internal Security Forces Hospital, Faculty of Medecine of Tunis, University of Tunis, Tunis, Tunisia.
³⁹ Cardiology Department, Bougatfa Hospital, Bizerte, Tunisia.
⁴⁰ Cardiology Department, Ibn El Jazzar Hospital, Kairouan, Tunisia.

^# Contributed equally.

PMID: 36053572
PMCID: PMC9482066
DOI: 10.2196/21878

Abstract

Background: This study was designed to evaluate the care of hypertensive patients in daily clinical practice in public and private centers in all Tunisian regions.

Objective: This study will provide us an overview of hypertension (HTN) management in Tunisia and the degree of adherence of practitioners to international recommendations.

Methods: This is a national observational cross-sectional multicenter study that will include patients older than 18 years with HTN for a duration of 4 weeks, managed in the public sector from primary and secondary care centers as well as patients managed in the private sector. Every participating patient signed a consent form. The study will exclude patients undergoing dialysis. The parameters that will be evaluated are demographic and anthropometric data, lifestyle habits, blood pressure levels, lipid profiles, treatment, and adherence to treatment. The data are collected via the web interface in the Dacima Clinical Suite.

Results: The study began on April 15, 2019 and ended on May 15, 2019. During this period, we included 25,890 patients with HTN. Data collection involved 321 investigators from 24 Tunisian districts. The investigators were doctors working in the private and public sectors.

Conclusions: Observational studies are extremely useful in improving the management of HTN in developing countries.

Trial registration: ClinicalTrials.gov NCT04013503; https://clinicaltrials.gov/ct2/show/NCT04013503.

International registered report identifier (irrid): DERR1-10.2196/21878.

Keywords: National Tunisian Registry; hypertension.

©Leila Abid, Rania Hammami, Salem Abdesselem, Selim Boudiche, Ben Slima Hédi, Khaled Sayahi, Amine Bahloul, Ikram Chamtouri, Salma Charfeddine, Lamia Rais, Meriem Drissa, Badreddine Ben Kaab, Hassen Ibn hadj amor, Lilia Ben Fatma, Riadh Garbaa, Sabrine Boukhris, Allouche Emna, Manel Ben Halima, Nesrine Amdouni, Shayma Ghorbel, Sabrine Soudani, Imen Khaled, Syrine Triki, Feten Bouazizi, Imen Jemai, Ouday Abdeljalil, Yemna Ammar, Amani Farah, Adnen Neji, Zeineb Oumaya, Sana Seghaier, Samir Mokrani, Hamza Thawaba, Hela Sarray, Khalil Ouaghlani, Houssem Thabet, Zeineb Mnif, Boujelben Masmoudi Fatma, Mohamed Sghaier, Roueida Khalifa, Sami Fourati, Yassmine Kammoun, Syrine Abid, Chiheb Hamza, Syrine Ben Jeddou, Lassaad Sabbah, Rim Lakhdhar, Najla Dammak, Tarak Sellami, Basma Herbegue, Alia Koubaa, Faten Triki, Tarek Ellouze, Aicha Hmoudi, Ikhlas Ben Ameur, Mohamed Mongi Boukhchina, Neila Abid, Wejdene Ouechtati, Nizar Nasrallah, Yousra Houidi, Fathia Mghaieth Zghal, Ghodhbane Elhem, Mounira Chayeb, Chenik Sarra, Samira Kaabachi, Nizar Saadaoui, Ines Ben Ameur, Moufida Affes, Sana Ouali, Mouna Chaker, Hela Naana, Dghim Meriem, Mourad Jarrar, Jihen Mnif, Ahmed Turki, Ihsen Zairi, Jamel Langar, Safa Dardouri, Imen Hachaichi, Rafik Chettaoui, Wajih Smat, Amel Chakroun, Khadija Mzoughi, Rachid Mechmeche, Afef Ben Halima, Sahar Ben Kahla Koubaa, Slim Chtourou, Maalej Mohamed abdelkader, Mohsen Ayari, Moufid Hadrich, Tlili Rami, Fares Azaiez, Imen Bouhlel, Samir Sahnoun, Habib Jerbi, Ben Mrad Imtinene, Leila Riahi, Mohamed Sahnoun, Abdelhamid Ben Jemaa, Amal Ben Salem, Bassem Rekik, Maroua Ben Doudou, Mohamed Rachid Boujnah, Anissa Joulak, Abid Omar, Rabie Razgallah, Milouchi Sami, Elyes Neffati, Habib Gamra, Soraya Ben Youssef, Wissem Sdiri, Nejeh Ben Halima, Youssef Ben Ameur, Salem Kachboura, Sondes Kraiem, Wafa Fehri, Lilia Zakhama, leila Bezdah, Mourali Mohamed Sami, Habiba Drissa, Mohamed Faouzi Maatouk, Samir Kammoun, Faouzi Addad. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 02.09.2022.

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Conflict of interest statement

Conflicts of Interest: None declared.

Figures

**Figure 1**
Protocol of population inclusion. HTN: hypertension.

See this image and copyright information in PMC

References

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Design and Rationale of the National Observational Multicentric Tunisian Registry of Hypertension: Protocol for Evaluating Hypertensive Patient Care in Clinical Practice

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Design and Rationale of the National Observational Multicentric Tunisian Registry of Hypertension: Protocol for Evaluating Hypertensive Patient Care in Clinical Practice

Authors

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Conflict of interest statement

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