Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Mar;6(1):e001376.
doi: 10.1136/bmjpo-2021-001376.

Risk calculator for advanced neonatal resuscitation

Edgardo Szyld  1 , Michael P Anderson  2 , Birju A Shah  3 , Charles C Roehr  4   5 , Georg M Schmölzer  6 , Jorge G Fabres  7 , Gary M Weiner  8
Affiliations

Risk calculator for advanced neonatal resuscitation

Edgardo Szyld et al. BMJ Paediatr Open. 2022 Mar.

Abstract

In order to predict which newborns will require advanced resuscitation (ANR), we developed an ANR risk calculator (calculator) using a bootstrap sample size of 52 973 from a case-control study of newborns ≥34 weeks gestation. Multivariable logistic regression coefficients were obtained for the 10 original risk factors and two interaction terms. The area under the receiving-operating characteristic curve predicting ANR was 0.9243. ANR prediction is improved by accounting for perinatal variables, beyond factors known prenatally. Prospective validation of this model is warranted in a clinical setting.

Keywords: Neonatology; Resuscitation.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
ROC curve of infants needing ANR from the multivariable logistic regression model based on the bootstrapped data set. Illustrated in the figure is a threshold value of 0.002 for the computed risk of ANR using the model that yields a sensitivity of 0.856 and a specificity of 0.751. ANR, advanced neonatal resuscitation; ROC, receiving-operating characteristic.
See this image and copyright information in PMC

References

    1. Niles DE, Cines C, Insley E, et al. . Incidence and characteristics of positive pressure ventilation delivered to newborns in a US tertiary academic Hospital. Resuscitation 2017;115:102–9. 10.1016/j.resuscitation.2017.03.035 - DOI - PubMed
    1. Szyld E, Aguilar A, Musante GA, et al. . Comparison of devices for newborn ventilation in the delivery room. J Pediatr 2014;165:234–9. 10.1016/j.jpeds.2014.02.035 - DOI - PubMed
    1. Almudeer A, McMillan D, O'Connell C, et al. . Do we need an Intubation-Skilled person at all high-risk deliveries? J Pediatr 2016;171:55–9. 10.1016/j.jpeds.2015.11.049 - DOI - PubMed
    1. Sawyer T, Lee HC, Aziz K. Anticipation and preparation for every delivery room resuscitation. Semin Fetal Neonatal Med 2018;23:312–20. 10.1016/j.siny.2018.06.004 - DOI - PubMed
    1. Berazategui JP, Aguilar A, Escobedo M, et al. . Risk factors for advanced resuscitation in term and near-term infants: a case-control study. Arch Dis Child Fetal Neonatal Ed 2017;102:F44–50. 10.1136/archdischild-2015-309525 - DOI - PubMed

LinkOut - more resources