Short-term Effectiveness of a Modified Osteotomy for Total Elbow Joint Replacement in Patients of Hemophilic Elbow Arthritis with Severe Flexion Contracture Deformity: A Three-Cases Series Report
- PMID: 36053811
- PMCID: PMC9531090
- DOI: 10.1111/os.13457
Short-term Effectiveness of a Modified Osteotomy for Total Elbow Joint Replacement in Patients of Hemophilic Elbow Arthritis with Severe Flexion Contracture Deformity: A Three-Cases Series Report
Abstract
Objective: To report the modified osteotomy and the short-term effectiveness of the total elbow joint replacement in patients of hemophilic elbow arthritis with severe flexion contracture deformity.
Methods: This study introduced the therapeutic approach of the total elbow joint replacement in patients of hemophilic elbow arthritis with severe flexion contracture deformity, and assessed the short-term effectiveness in three cases (three elbows) of end-stage hemophilic elbow arthritis admitted from October 2020 to December 2020. The included patients were all diagnosed with hemophilia A (factor VII deficiency), accompanied by severe bilateral elbow joint flexion contracture, which seriously affects daily life and requires surgical intervention. Clinical data and follow-up results were analyzed before total elbow arthroplasty and 1, 3, and 6 months postoperatively. Pre- and postoperative range of motion, pain score, and function score were compared, and intraoperative and postoperative complications are reported.
Results: All three patients were male, with an average age of 31 years. The main clinical manifestations were bilateral elbow arthritis with flexion contracture. Two of the patients underwent right elbow replacement, and one patient underwent left elbow replacement. All cases were followed up for 6 months postoperatively. No incision infection or ulnar nerve injury occurred. Postoperative triceps brachii muscle strength was slightly weakened compared with preoperative muscle strength. Average elbow flexion and extension range of motion was 60° (30°-100°) preoperatively and increased to 127° (110°-140°) postoperatively; rotational range of motion of the affected forearm was 47° (10°-85°) preoperatively and increased to 117° postoperatively. The mean visual analogue scale (VAS) was 6 (5-8) preoperatively and decreased to 3 (2-4) postoperatively. The mean MEPS score was 62 (55-75) and increased to 87 (80-95) postoperatively. During the follow-up, anteroposterior and lateral radiographs showed no signs of prosthesis loosening in the elbow.
Conclusions: For severe hemophilic elbow arthritis patients, the short-term treatment effect of total elbow replacement is good, following the strict adherence to the surgical indications and proper preparation for the perioperative period. The modified osteotomy can fully expose the visual field and reduce complications of ulnar nerve injury. The long-term effects need to be study future.
Keywords: Elbow joint function; Hemophilia A; Hemophilic elbow arthritis; Pain score; Total elbow joint replacement.
© 2022 The Authors. Orthopaedic Surgery published by Tianjin Hospital and John Wiley & Sons Australia, Ltd.
Figures




Similar articles
-
[Effectiveness of total elbow arthroplasty via olecranon osteotomy approach].Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2022 Nov 15;36(11):1363-1368. doi: 10.7507/1002-1892.202205116. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2022. PMID: 36382453 Free PMC article. Chinese.
-
Does an Internal Joint Stabilizer and Standardized Protocol Prevent Recurrent Instability in Complex Persistent Elbow Instability?Clin Orthop Relat Res. 2022 Jul 1;480(7):1354-1370. doi: 10.1097/CORR.0000000000002159. Epub 2022 Mar 10. Clin Orthop Relat Res. 2022. PMID: 35266916 Free PMC article.
-
[Spinal wedged osteotomy combined with total hip arthroplasty for kyphosis and severe hip flextion contracture caused by ankylosing spondylitis].Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2014 Aug;28(8):942-6. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2014. PMID: 25417303 Chinese.
-
Primary Souter-Strathclyde total elbow prosthesis in rheumatoid arthritis. Surgical technique.J Bone Joint Surg Am. 2005 Mar;87 Suppl 1(Pt 1):67-77. doi: 10.2106/JBJS.D.02734. J Bone Joint Surg Am. 2005. PMID: 15743848 Review.
-
Total elbow arthroplasty in patients with rheumatoid arthritis.Bone Joint J. 2020 Aug;102-B(8):967-980. doi: 10.1302/0301-620X.102B8.BJJ-2019-1465.R1. Bone Joint J. 2020. PMID: 32731835 Free PMC article.
Cited by
-
Managing Surgical Risks in Hemophilic Elbow Arthropathy: An In-Depth Case Study and Literature Review.Healthcare (Basel). 2024 Sep 5;12(17):1776. doi: 10.3390/healthcare12171776. Healthcare (Basel). 2024. PMID: 39273799 Free PMC article.
-
Total elbow arthroplasty for hemophilic osteoproliferative elbow arthritis with severe flexion contracture: A case report.SAGE Open Med Case Rep. 2023 Dec 13;11:2050313X231216597. doi: 10.1177/2050313X231216597. eCollection 2023. SAGE Open Med Case Rep. 2023. PMID: 38106466 Free PMC article.
References
-
- Dale TM, Saucedo JM, Rodriguez‐Merchan EC. Total elbow arthroplasty in haemophilia. Haemophilia. 2018;24(4):548–56. - PubMed
-
- Iorio A, Stonebraker JS, Chambost H, Makris M, Coffin D, Herr C, et al. Establishing the prevalence and prevalence at birth of hemophilia in males: a meta‐analytic approach using national registries. Ann Intern Med. 2019;171(8):540–6. - PubMed
-
- Mannucci PM, Tuddenham EG. The hemophilias—from royal genes to gene therapy. N Engl J Med. 2001;344(23):1773–9. - PubMed
-
- Arnold WD, Hilgartner MW. Hemophilic arthropathy. Current concepts of pathogenesis and management. J Bone Joint Surg Am. 1977;59(3):287–305. - PubMed
-
- Utukuri MM, Goddard NJ. Haemophilic arthropathy of the elbow. Haemophilia. 2005;11(6):565–70. - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
Medical