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Comment
. 2022 Sep 1;29(9):1285-1287.
doi: 10.1016/j.stem.2022.08.004.

Uncovering the origins and lineage markers of human heart fields

Matthew Miyamoto  1 , Chulan Kwon  2
Affiliations
Comment

Uncovering the origins and lineage markers of human heart fields

Matthew Miyamoto et al. Cell Stem Cell. .

Abstract

In this issue of Cell Stem Cell, Yang et al. devise a protocol for induction and differentiation of human heart-field precursors, drawing on inspiration from in vivo development. Intricate computational analyses uncovered conserved factors governing heart-field segregation, which facilitate enhanced study of human heart development and disease in the dish.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Figures

Figure 1.
Figure 1.. Pre-heart-field cell induction and differentiation in human pluripotent stem cell culture
hPSC, human pluripotent stem cells; FHF, first heart field; aSHF, anterior second heart field; pSHF, posterior second heart field; CM, cardiomyocyte; LV, left ventricular; AVC, atrioventricular canal; RV, right ventricular; OFT, outflow tract; A, atrial; SV, sinus venosus; RA, retinoid acid.
See this image and copyright information in PMC

Comment on

References

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