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Comment
. 2022 Sep 1;29(9):1287-1289.
doi: 10.1016/j.stem.2022.08.010.

Fission impossible: Mitochondrial dynamics direct muscle stem cell fates

Ji-Hyung Lee  1 , Foteini Mourkioti  2
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Comment

Fission impossible: Mitochondrial dynamics direct muscle stem cell fates

Ji-Hyung Lee et al. Cell Stem Cell. .
Free article

Abstract

Muscle stem cells (MuSCs) exhibit different metabolic profiles depending on their activity, however the mechanisms by which mitochondria affect MuSC fate has been understudied. In this issue of Cell Stem Cell, Hong et al. (2022) and Baker et al. (2022) demonstrate that defects in mitochondrial dynamics hinder proper MuSC activation and impair muscle regeneration.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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