Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Aug 19:13:950457.
doi: 10.3389/fphar.2022.950457. eCollection 2022.

Potential therapeutics against neurological disorders: Natural products-based drugs

Abdur Rauf  1 , Md Mominur Rahman  2
Affiliations
Review

Potential therapeutics against neurological disorders: Natural products-based drugs

Abdur Rauf et al. Front Pharmacol. .

Abstract

Neurodegenerative disorders, which are defined by the breakdown of neurons over time, are affecting an increasing number of people. Stroke, Alzheimer's, Parkinson's, Multiple Sclerosis, Migraine, and Amyotrophic Lateral Sclerosis are just a few examples of brain disorders that have no cure. Besides, there is a huge demand for drugs that can cure the diseases mentioned above because the majority of the medications we use to treat them only alleviate diseases. Different neurological disorders have responded satisfactorily to the pharmacological effects of medicinal plants. Despite the numerous multiple types of plants in the world, only a small number of them have been investigated for neurological disorders. As a result, there are many opportunities in this area for further research on plants and their bioactive chemicals. The search for natural therapeutic alternatives that promote faster healing and adverse effects avoidance has gained popularity in recent years. The aim of this mini-review is to explore some natural products that have strong therapeutic effects on neurodegenerative disorders such as Stroke, Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis, Migraine, Amyotrophic Lateral Sclerosis, and others. We have also shown the safety of natural products to improve their appropriate usage in neurological disorders from recent literature.

Keywords: Malnutrition; drugs; natural products; neurological disorders; potential therapeutics.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

    1. Bhattacharya T., Soares G. A. B. E., Chopra H., Rahman M. M., Hasan Z., Swain S. S., et al. (2022). Applications of Phyto-Nanotechnology for the Treatment of Neurodegenerative Disorders. Materials 15, 804. 10.3390/MA15030804 - DOI - PMC - PubMed
    1. Clevenger S. S., Malhotra D., Dang J., Vanle B., IsHak W. W. (2017). The Role of Selective Serotonin Reuptake Inhibitors in Preventing Relapse of Major Depressive Disorder. Ther. Adv. Psychopharmacol. 8, 49–58. 10.1177/2045125317737264 - DOI - PMC - PubMed
    1. Ferrari A. (2022). Global, Regional, and National Burden of 12 Mental Disorders in 204 Countries and Territories, 1990–2019: a Systematic Analysis for the Global Burden of Disease Study 2019. Lancet Psychiatry 9, 137–150. 10.1016/S2215-0366(21)00395-3 - DOI - PMC - PubMed
    1. Hartman L., Jenkinson C., Morley D. (2020). Young People’s Response to Parental Neurological Disorder: A Structured Review. Adolesc. Health Med. Ther. 11, 39–51. 10.2147/AHMT.S237807 - DOI - PMC - PubMed
    1. Karim N., Abdelhalim H., Gavande N., Khan I., Khan H. (2018). Natural Products as an Emerging Therapeutic Alternative in the Treatment of Neurological Disorders. Evid. Based. Complement. Altern. Med. 2018, 3056847. 10.1155/2018/3056847 - DOI - PMC - PubMed