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Review
. 2022 Aug 5;9(2):59-69.
doi: 10.14338/IJPT-22-00017. eCollection 2022 Fall.

Fast and Furious: Fast Neutron Therapy in Cancer Treatment

Konstantin Gordon  1   2 , Igor Gulidov  2 , Timur Fatkhudinov  1 , Sergey Koryakin  2 , Andrey Kaprin  1   2
Affiliations
Review

Fast and Furious: Fast Neutron Therapy in Cancer Treatment

Konstantin Gordon et al. Int J Part Ther. .

Abstract

Fast neutron therapy has been used for decades. In conjunction with recent advances in photonic techniques, fast neutrons are no longer of much oncologic interest, which is not unequivocally positive, given their undoubted therapeutic value. This mini-review recalls the history of medical research on fast neutrons, considers their physical and radiobiological properties alongside their benefits for cancer treatment, and discusses their place in modern radiation oncology.

Keywords: cancer treatment; fast neutrons; radiation therapy.

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Conflict of interest statement

Conflicts of Interest: The authors have no relevant conflicts of interest to disclose.

References

    1. Durante M. Proton beam therapy in Europe: more centres need more research. Br J Cancer . 2019;120:777–8. - PMC - PubMed
    1. De Ruysscher D, Mark Lodge M, Jones B, Brada M, Munro A, Jefferson T, Pijls-Johannesma M. Charged particles in radiotherapy: a 5-year update of a systematic review. Radiother Oncol . 2012;103:5–7. - PubMed
    1. Suit H, DeLaney T, Goldberg S, Paganetti H, Clasie B, Gerweck L, Niemierko A, Hall E, Flanz J, Hallman J, Trofimov A. Proton vs carbon ion beams in the definitive radiation treatment of cancer patients. Radiother Oncol . 2010;95:3–22. - PubMed
    1. Chadwick J. Possible existence of a neutron. Nature . 1932;129:312.
    1. Lawrence JH, Aebersold PC, Lawrence EO. Comparative effects of X-rays and neutrons on normal and tumor tissue. Proc Natl Acad Sci U S A . 1936;22:543–57. - PMC - PubMed

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