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Comparative Study
. 1987 Apr;31(4):650-2.
doi: 10.1128/AAC.31.4.650.

In vitro activity of paldimycin (U-70138F) against gram-positive bacteria isolated from patients with cancer

K V Rolston, B LeBlanc, D H Ho, G P Bodey
Comparative Study

In vitro activity of paldimycin (U-70138F) against gram-positive bacteria isolated from patients with cancer

K V Rolston et al. Antimicrob Agents Chemother. 1987 Apr.

Abstract

The in vitro activity of paldimycin, a novel antimicrobial agent, was compared with that of vancomycin against 306 gram-positive isolates (representing 12 bacterial species) obtained from patients with cancer. Paldimycin had lower MICs for 90% of isolates than vancomycin did against most isolates tested. Its activity, however, was medium and pH dependent, being greatest in Nutrient broth at a pH of 6.8.

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References

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