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Review
. 2022 Aug 17:13:962619.
doi: 10.3389/fmicb.2022.962619. eCollection 2022.

Current status of pesticide effects on environment, human health and it's eco-friendly management as bioremediation: A comprehensive review

Vinay Mohan Pathak  1 , Vijay K Verma  1 , Balwant Singh Rawat  2 , Baljinder Kaur  3 , Neelesh Babu  4 , Akansha Sharma  5 , Seeta Dewali  6 , Monika Yadav  7 , Reshma Kumari  8 , Sevaram Singh  9   10 , Asutosh Mohapatra  11 , Varsha Pandey  12 , Nitika Rana  13 , Jose Maria Cunill  14
Affiliations
Review

Current status of pesticide effects on environment, human health and it's eco-friendly management as bioremediation: A comprehensive review

Vinay Mohan Pathak et al. Front Microbiol. .

Abstract

Pesticides are either natural or chemically synthesized compounds that are used to control a variety of pests. These chemical compounds are used in a variety of sectors like food, forestry, agriculture and aquaculture. Pesticides shows their toxicity into the living systems. The World Health Organization (WHO) categorizes them based on their detrimental effects, emphasizing the relevance of public health. The usage can be minimized to a least level by using them sparingly with a complete grasp of their categorization, which is beneficial to both human health and the environment. In this review, we have discussed pesticides with respect to their global scenarios, such as worldwide distribution and environmental impacts. Major literature focused on potential uses of pesticides, classification according to their properties and toxicity and their adverse effect on natural system (soil and aquatic), water, plants (growth, metabolism, genotypic and phenotypic changes and impact on plants defense system), human health (genetic alteration, cancer, allergies, and asthma), and preserve food products. We have also described eco-friendly management strategies for pesticides as a green solution, including bacterial degradation, myco-remediation, phytoremediation, and microalgae-based bioremediation. The microbes, using catabolic enzymes for degradation of pesticides and clean-up from the environment. This review shows the importance of finding potent microbes, novel genes, and biotechnological applications for pesticide waste management to create a sustainable environment.

Keywords: DNA damage; allergy; biodegradation; cancer; pesticides; plants; water.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Percentage distribution of pesticides (Nicolopoulou-Stamati et al., 2016; Alengebawy et al., 2021).
FIGURE 2
FIGURE 2
Thematic diagram of the synthesis, production, uses, effects, and eco-friendly management of pesticides.
FIGURE 3
FIGURE 3
Classification of pesticides (Jayaraj et al., 2016; Hassaan and El Nemr, 2020; Malhotra et al., 2021; Souto et al., 2021; Parra-Arroyo et al., 2022).
FIGURE 4
FIGURE 4
Major molecular mechanisms associated with pesticides-induced carcinogenesis.
See this image and copyright information in PMC

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