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Review
. 2022 Jun 18;21(1):e127030.
doi: 10.5812/ijpr-127030. eCollection 2022 Dec.

A Comprehensive Review of the Role of Complementary and Dietary Medicines in Eradicating Helicobacter pylori

Saeed Abdi  1 , Sara Ataei  2 , Maede Abroon  3 , Pantea Majma Sanaye  3 , Mohammad Abbasinazari  4 , Amir Farrokhian  4
Affiliations
Review

A Comprehensive Review of the Role of Complementary and Dietary Medicines in Eradicating Helicobacter pylori

Saeed Abdi et al. Iran J Pharm Res. .

Abstract

Antibiotic-resistant Helicobacter pylori isolates have become a global concern. The standard triple or quadruple therapies have recently become the most effective protocol for eradicating H. pylori in the gastrointestinal tract. There is evidence regarding the impact of different complementary or dietary supplements on H. pylori eradication. This review article intended to search electronic bibliographic databases for any clinical studies that evaluated the use of any herbal or dietary supplements to eradicate H. pylori up to June 2021. A total of 20 human studies met our criteria and were reviewed. Although some herbal medicines have shown their efficacy and safety in eradicating H. pylori in different clinical trials, more randomized blind, placebo-controlled human trials with a large sample size must be performed to extend our knowledge.

Keywords: Clinical Trials; Gastrointestinal Disorders; Herbal Medicines; Medical Databases; Nutraceuticals.

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Conflict of interest statement

Conflict of Interests: None.

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Figure 1.. Search strategy
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