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Case Reports
. 2022 Aug 31;9(8):e00836.
doi: 10.14309/crj.0000000000000836. eCollection 2022 Aug.

Esophageal Stricture Caused by CMV in a Non-HIV-Infected Renal Transplant Patient

Tamera C Tennant  1 , Samiksha Pandey  1 , Ahmed I Edhi  2 , Mihaela Batke  2
Affiliations
Case Reports

Esophageal Stricture Caused by CMV in a Non-HIV-Infected Renal Transplant Patient

Tamera C Tennant et al. ACG Case Rep J. .

Abstract

Esophageal stricture due to cytomegalovirus (CMV) infection is an uncommon pathology, with most reported cases occurring in patients infected with human immunodeficiency virus. We report a renal transplant patient who presented with progressive dysphagia and weight loss for 2 years. Endoscopic examination revealed a long esophageal stricture with a necrotic lesion but no typical CMV esophageal ulcers; immunostains were positive for CMV. Dysphagia resolved after treatment with ganciclovir and serial esophageal dilations. We are presenting the first case of esophageal stricture due to CMV esophagitis in a renal transplant patient without human immunodeficiency virus infection and are reviewing current literature.

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Figures

Figure 1.
Figure 1.
Esophagogastroduodenoscopy revealed a 5–6-mm distal esophageal stricture.
Figure 2.
Figure 2.
Focal necrotic lesion just proximal to the stricture.
See this image and copyright information in PMC

References

    1. Wilcox CM. Esophageal strictures complicating ulcerative esophagitis in patients with AIDS. Am J Gastroenterol. 1999;94(2):339–43. - PubMed
    1. Mansfield BS, Savage-Reid MJ, Moyo J, et al. Cytomegalovirus-associated esophageal stricture as a manifestation of the immune reconstitution inflammatory syndrome. IDCases. 2020;21:e00795. - PMC - PubMed
    1. Sheth A, Boktor M, Diamond K, et al. Complete esophageal obliteration secondary to cytomegalovirus in AIDS patient. Dis Esophagus. 2010;23(6):E32–4. - PubMed
    1. Goodgame RW, Ross PG, Kim HS, et al. Esophageal stricture after cytomegalovirus ulcer treated with ganciclovir. J Clin Gastroenterol. 1991;13(6):678–81. - PubMed
    1. Olmos M, Sanchez Basso A, Battaglia M, et al. Esophageal strictures complicating cytomegalovirus ulcers in patients with AIDS. Endoscopy. 2001;33(9):822. - PubMed

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