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. 2022 Aug 28;10(4):757-769.
doi: 10.14218/JCTH.2022.00147. Epub 2022 Apr 29.

Guidelines for the Management of Cholestatic Liver Diseases (2021)

Lungen Lu  1 ; Chinese Society of Hepatology and Chinese Medical Association
Affiliations

Guidelines for the Management of Cholestatic Liver Diseases (2021)

Lungen Lu et al. J Clin Transl Hepatol. .

Abstract

In 2015, the Chinese Society of Hepatology and the Chinese Society of Gastroenterology issued a consensus statement on the diagnosis and management of cholestatic liver diseases. More clinical data on this topic have appeared during recent years. The Autoimmune Liver Disease Group of the Chinese Society of Hepatology organized an expert group to review recent evidence and provide an update to these previous guidelines. Herein, we provide 22 recommendations as a working reference for the management of cholestatic liver diseases by clinical practitioners.

Keywords: Cholestatic liver disease; Diagnosis; Practice guidelines; Therapeutics.

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Conflict of interest statement

LL has been an associate editor of Journal of Clinical and Translational Hepatology since 2013. HY has been an editorial board member of Journal of Clinical and Translational Hepatology since 2021. YH has been an editorial board member of Journal of Clinical and Translational Hepatology since 2013. LW and JJ have been an executive associate editor of Journal of Clinical and Translational Hepatology since 2021. The other authors have no conflict of interests related to this publication.

Figures

Fig. 1
Fig. 1. Location of injuries that lead to cholestatic liver disease.
BRIC, benign recurrent intra-hepatic cholestasis; ICP, intrahepatic cholestasis of pregnancy; IgG4-SC, IgG4-related sclerosing cholangitis; PBC, primary biliary cholangitis; PFIC, progressive familial intrahepatic cholestasis; PSC, primary sclerosing cholangitis; SSC, secondary sclerosing cholangitis.
Fig. 2
Fig. 2. Recommended procedures for diagnosis of cholestatic liver diseases.
ALP, alkaline phosphatase; AMA, anti-mitochondrial antibodies; ANA, antinuclear antibodies; ERCP, endoscopic retrograde cholangiopancreatography; EUS, endoscopic ultrasound; GGT, gamma-glutamyl transferase; IgG4, immunoglobulin G4; PSC, primary sclerosing cholangitis.
See this image and copyright information in PMC

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