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Comment
. 2023 Feb;113(2):219-220.
doi: 10.1002/cpt.2726. Epub 2022 Sep 5.

Response to "CYP450 3A4/5 Containment During SARS-CoV-2 Infection"

Edouard Charles Le Carpentier  1 , Emmanuel Canet  2 , Damien Masson  3 , Ronan Bellouard  1   4 , Matthieu Grégoire  1   4
Affiliations
Comment

Response to "CYP450 3A4/5 Containment During SARS-CoV-2 Infection"

Edouard Charles Le Carpentier et al. Clin Pharmacol Ther. 2023 Feb.
No abstract available

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Conflict of interest statement

The authors declared no competing interests for this work.

Figures

Figure 1
Figure 1
Impact of inflammation on tacrolimus concentrations and monitoring. The curved lines represent the longitudinal follow‐up of tacrolimus concentrations. The dots represent the daily doses administered. The histograms represent the C‐reactive protein concentrations. The straight full lines represent the date of positive SARS‐CoV‐2 reverse transcription polymerase chain reaction. The dotted lines represent the beginning of symptoms. The dashed lines represent the date of transplant. The black double arrows represent the hospitalization in the ICU. The gray double arrow represents the administration of a drug that could inhibit the CYP450 3A4/5 activity. (a) Representation of the axis label. (b–h) Representation of the longitudinal follow‐up of tacrolimus concentrations for seven patients hospitalized in Nantes Hospital. CYP450 3A 4/5, cytochrome P450 3A 4/5 isozymes; D, Day; ICU, intensive care unit; SARS‐CoV‐2, severe acute respiratory syndrome coronavirus 2.
See this image and copyright information in PMC

Comment on

References

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