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Case Reports
. 2022 Aug 26:2022:7777445.
doi: 10.1155/2022/7777445. eCollection 2022.

A Case Report of Severe Coagulopathy in Antenatal COVID-19

Anna Sand  1   2 , Roza Chaireti  3   4 , Maria Sennström  1   2 , Karin Pettersson  2   5 , Maria Magnusson  3   4   5
Affiliations
Case Reports

A Case Report of Severe Coagulopathy in Antenatal COVID-19

Anna Sand et al. Case Rep Obstet Gynecol. .

Abstract

Pregnancy is a naturally occurring hypercoagulable state, and COVID-19 can cause profound changes in the coagulation system associated with thromboinflammation. We report a case of a pregnant woman with moderate symptoms of COVID-19 and a severe coagulopathy with unexpected low levels of fibrinogen and factor VIII as well as atypical thrombelastometry results. She developed a severe placental dysfunction with intrauterine fetal distress and perinatal death. The case did not fulfil the criteria for preeclampsia or sepsis, and the adverse outcome was assessed as a direct effect of the COVID-19 infection with placental insufficiency, despite absence of serious maternal pulmonary symptoms. Atypical persistent coagulopathy may serve as an important marker of a serious obstetrical situation in COVID-19.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

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