Staging the bipolar disorders: Are early stages at too early a stage for intervention?
- PMID: 36065503
- PMCID: PMC10946882
- DOI: 10.1111/bdi.13256
Staging the bipolar disorders: Are early stages at too early a stage for intervention?
Abstract
Objectives: A number of staging models have been generated for the bipolar disorders, which include pre-onset as well as post-onset stages. Some models propose treatments for those at the pre-onset stage, a recommendation which is critiqued here.
Methods: Several exemplar staging models are overviewed, and a critique is provided.
Results: The critique argues against intervention at a pre-onset stage, in light of there being limited risk factors, unquantified sensitivity and specificity data for most putative onset illness risk factors, and thus there is the risk of overtreatment. Also, it is possible that many of the recommended interventions for those at risk of a bipolar disorder may have general non-specific benefits for those at risk.
Conclusions: While retaining a pre-onset phase in the staging model, it would appear wiser for it to not be populated with recommended interventions until they have a firmer empirical base.
Keywords: bipolar disorder; interventions; staging.
© 2022 The Author. Bipolar Disorders published by John Wiley & Sons Ltd.
Conflict of interest statement
None.
Comment in
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Early interventions for youth at high risk for bipolar disorder.Bipolar Disord. 2022 Dec;24(8):826-827. doi: 10.1111/bdi.13266. Epub 2022 Nov 16. Bipolar Disord. 2022. PMID: 36349413 Free PMC article. No abstract available.
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Gordon Parker: Staging the bipolar disorders: Are early stages at too early a stage for intervention?Bipolar Disord. 2022 Dec;24(8):828-829. doi: 10.1111/bdi.13278. Epub 2022 Dec 1. Bipolar Disord. 2022. PMID: 36433661 Free PMC article. No abstract available.
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Staging the bipolar disorders: Are early stages too early a stage for intervention?Bipolar Disord. 2023 Feb;25(1):76-78. doi: 10.1111/bdi.13281. Epub 2022 Dec 10. Bipolar Disord. 2023. PMID: 36479794 No abstract available.
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Early clinical staging: Why does it matter, and what do we know?Bipolar Disord. 2023 Feb;25(1):79-81. doi: 10.1111/bdi.13290. Epub 2023 Jan 26. Bipolar Disord. 2023. PMID: 36591646 No abstract available.
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