Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Nov;43(6):425-433.
doi: 10.1007/s00292-022-01103-2. Epub 2022 Sep 7.

[Diagnostic problems in testicular tumours in consultant pathology : A practical guide]

[Article in German]
Affiliations
Review

[Diagnostic problems in testicular tumours in consultant pathology : A practical guide]

[Article in German]
Felix Bremmer et al. Pathologie (Heidelb). 2022 Nov.

Abstract

The great variety of pathological patterns in germ cell tumours, especially in yolk sac tumours but also the possibility of somatic-type malignancies, can complicate daily diagnosis. For the correct diagnosis, knowledge of morphological aspects and additional immunohistochemical staining can be helpful. Also, rare entities like sex cord stromal tumours, tumours of testicular adnexa or mesenchymal tumours of the spermatic cord can be diagnostically challenging.

Die große Vielfalt der histologischen Muster von Keimzelltumoren, insbesondere beim Dottersacktumor, aber auch das Phänomen der somatischen Malignität können die tägliche Diagnostik komplizieren. Verschiedene morphologische Aspekte und immunhistochemische Zusatzuntersuchungen können bei der Diagnosefindung hilfreich sein. Auch das Spektrum seltener Entitäten wie Gonadenstromatumoren, testikuläre Adnextumoren und Weichgewebstumoren des Samenstrangs können zu einer diagnostischen Herausforderung werden.

Keywords: Germ cell tumours; Immunohistochemical algorithm; Sex cord stromal tumours; Somatic-type malignancies; Tumours of the testicular adnexa.

PubMed Disclaimer

Similar articles

References

Literatur

    1. Ahmed T, Bosl GJ, Hajdu SI (1985) Teratoma with malignant transformation in germ cell tumors in men. Cancer 56:860–863. https://doi.org/10.1002/1097-0142(19850815)56:4<860::aid-cncr28205604... - DOI
    1. Alvarado-Cabrero I, Hernández-Toriz N, Paner GP (2014) Clinicopathologic analysis of choriocarcinoma as a pure or predominant component of germ cell tumor of the testis. Am J Surg Pathol 38:111–118. https://doi.org/10.1097/PAS.0b013e3182a2926e - DOI - PubMed
    1. Angulo JC, González J, Rodríguez N et al (2009) Clinicopathological study of regressed testicular tumors (apparent extragonadal germ cell neoplasms). J Urol 182(5):2303–2310 - DOI
    1. Anheuser P, Kranz J, Stolle E et al (2019) Testicular epidermoid cysts: a reevaluation. BMC Urol 19:52. https://doi.org/10.1186/s12894-019-0477-1 - DOI - PubMed - PMC
    1. Balzer BL, Ulbright TM (2006) Spontaneous regression of testicular germ cell tumors: an analysis of 42 cases. Am J Surg Pathol 30:858–865. https://doi.org/10.1097/01.pas.0000209831.24230.56 - DOI - PubMed

MeSH terms

LinkOut - more resources