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Review
. 2022 Sep 7;22(1):279.
doi: 10.1186/s12935-022-02696-7.

Camels' biological fluids contained nanobodies: promising avenue in cancer therapy

Nouf S Al-Numair  1   2 , Abdulrahman Theyab  3   4 , Faisal Alzahrani  5   6 , Anwar M Shams  7 , Ibrahim O Al-Anazi  8 , Atif Abdulwahab A Oyouni  9   10 , Osama M Al-Amer  11 , Charalampos Mavromatis  12 , Islam M Saadeldin  13 , Wed A Abdali  9 , Yousef M Hawsawi  14   15
Affiliations
Review

Camels' biological fluids contained nanobodies: promising avenue in cancer therapy

Nouf S Al-Numair et al. Cancer Cell Int. .

Erratum in

Abstract

Cancer is a major health concern and accounts for one of the main causes of death worldwide. Innovative strategies are needed to aid in the diagnosis and treatment of different types of cancers. Recently, there has been an evolving interest in utilizing nanobodies of camel origin as therapeutic tools against cancer. Nanotechnology uses nanobodies an emerging attractive field that provides promises to researchers in advancing different scientific sectors including medicine and oncology. Nanobodies are characteristically small-sized biologics featured with the ability for deep tissue penetration and dissemination and harbour high stability at high pH and temperatures. The current review highlights the potential use of nanobodies that are naturally secreted in camels' biological fluids, both milk and urine, in the development of nanotechnology-based therapy for treating different typesQuery of cancers and other diseases. Moreover, the role of nano proteomics in the invention of novel therapeutic agents specifically used for cancer intervention is also illustrated.

Keywords: And nano proteomics; Arabian camelid; Biological fluids; Cancers; Diagnosis; Nanobodies; Therapeutic agents.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Nanobodies applications
Fig. 2
Fig. 2
The diversity and distribution of Camels in Saudi Arabia
Fig. 3
Fig. 3
The effect of camel’s secretion on different diseases
Fig. 4
Fig. 4
The impact of Camel’s secretion on overall survival in several diseases
See this image and copyright information in PMC

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