Adenoid Ameloblastoma with Dentinoid: A systematic review

Abstract

This article aimed to collectively present the demographic, clinical, radiographic and histopathological features as well as the treatment performed along with its outcome for all the cases of adenoid ameloblastoma with dentinoid (AAD) reported in scientific literature till date. Ameloblastoma and adenomatoid odontogenic tumours are the most common odontogenic neoplasms. However, AAD, a hybrid variant of the two lesions, is found to be extremely rare. The lesion comprises of characteristic histopathological features of ameloblastoma and adenomatoid odontogenic tumour and shares certain clinical characteristics with either of the entities. AAD may be considered to be present at the more aggressive end of spectrum of benign odontogenic neoplasms. Owing to the frequent tendency of the lesions to be underdiagnosed, careful histopathological screening of submitted biopsies is warranted. With the increase in number of reported cases in the recent years, it is likely to be included as a separate entity in the upcoming World Health Organization classification.

Keywords: Adenoameloblastoma; Adenomatoid Odontogenic Tumor; Immunohistochemistry; Odontogenic Tumors.

Figure 1

PRISMA flow chart indicating selection process of articles for final qualitative synthesis in the present systematic review.

Figure 2

Number of reported cases of adenoid ameloblastoma with dentinoid belonging to various age groups.