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Case Reports
. 2022 Aug 28:2022:2324212.
doi: 10.1155/2022/2324212. eCollection 2022.

Coexistence of Pemphigus Vulgaris and Lichen Planus following COVID-19 Vaccination

Zeinab Aryanian  1   2 , Kamran Balighi  1   3 , Arghavan Azizpour  1   3 , Kambiz Kamyab Hesari  1   4 , Parvaneh Hatami  1
Affiliations
Case Reports

Coexistence of Pemphigus Vulgaris and Lichen Planus following COVID-19 Vaccination

Zeinab Aryanian et al. Case Rep Dermatol Med. .

Abstract

SARS-CoV-2 vaccines were approved without long-term monitoring due to emergent situation and might have several side effects. Herein, we describe the first case with development of both LP and PV following COVID-19 vaccination. Immunological alteration due to COVID-19 vaccination and its potential role in triggering autoimmune disorders were also dealt with.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
Oral mucosal lesions (a) and scalp erosion (b) due to pemphigus and hyperpigmented macules on ear (c) and cheek (d) due to lichen planus pigmentosus following COVID-19 vaccination.
Figure 2
Figure 2
Suprabasal epidermal acantholysis and cleft containing inflammatory cells and rounded acantholytic cells with intensely eosinophilic cytoplasm and a perinuclear halo. DIF shows intercellular deposition throughout the epidermis compatible with diagnosis of PV (a, b). Hyperkeratosis, atrophic epidermis with vacuolar alteration of the basal cell layer, and pigmentary incontinence and negative. DIF, compatible with diagnosis of LP pigmentosus (c, d)
Figure 3
Figure 3
The exact time points of events.
See this image and copyright information in PMC

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