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. 2022 Dec;43(12):6865-6870.
doi: 10.1007/s10072-022-06321-3. Epub 2022 Sep 8.

Trends of recanalization therapies and state of art for ischemic stroke treatment in Campania region, Italy

Emanuele Spina #  1   2 , Paolo Candelaresi #  3 , Giampiero Volpe  4 , Florindo D'Onofrio  5 , Daniele Spitaleri  5 , Gioacchino Martusciello  6 , Giovanni Piccirillo  6 , Francesco Briganti  7 , Mario Muto  8 , Michele Feleppa  9 , Marco Sparaco  9 , Andrea Manto  10 , Teresa Cuomo  11 , Salvatore Ascione  12 , Patrizia Ripa  12 , Daniele Giuseppe Romano  13 , Vincenzo Andreone  3 , Fiore Manganelli  14 , Rosa Napoletano  4
Affiliations

Trends of recanalization therapies and state of art for ischemic stroke treatment in Campania region, Italy

Emanuele Spina et al. Neurol Sci. 2022 Dec.

Abstract

Background: According to the last Italian report by the Ministry of Health in 2018, the estimated number of acute ischemic strokes (AIS) in Campania is 10,000/year, with an expected number of 1390 intravenous thrombolysis (IVT) and 694 mechanical thrombectomies (MT). In 2017, only 1.5% of expected patients received IVT and 0.2% MT. This study analyzed the trend of IVT and MT in 2019-2020 and depicted the state of art of Stroke Care in Campania.

Methods: From the regional health task force, we obtained the hospital discharge forms from all private and public hospitals in Campania; we selected patients with a principal diagnosis of AIS and measured the rate of patients admitted to neurology units and the rate of IVT, MT, and IVT + MT for both 2019 and 2020.

Results: In 2019, we observed 4817 admissions for AIS; 2858/4817 (59.3%) patients were admitted to neurology units. Out of 4817 patients, 192 received IVT, 165 MT, and 131 IVT + MT (488 treated patients; 10.1%). In 2020, we observed 4129 admissions for AIS; 2502/4129 (62.7%) patients were admitted to neurology units. Out of 4129 patients, 198 received IVT, 250 MT, and 180 IVT + MT (628 treated patients; 15.2%). These results showed that despite a reduction of AIS admissions in 2020, the relative and absolute rate of recanalization treatments increased. However, the number of patients who were not admitted to neurology units nor received acute treatments remained dramatically high.

Conclusion: Despite the development of acute treatments, the Campania Stroke Network still needs significative efforts to improve.

Keywords: Campania; Epidemiology; Recanalization therapies; Stroke; Trend.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Reperfusion therapies in 2017, 2019, and 2020
Fig. 2
Fig. 2
Percent of stroke unit of 1st level on the expected total from the Regional Act
Fig. 3
Fig. 3
Percent of stroke unit of 2nd level on the expected total from the Regional Act
Fig. 4
Fig. 4
Percent of high-intensive monitored beds in neurology units on the expected total
See this image and copyright information in PMC

References

    1. GBD 2019 Stroke Collaborators Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol. 2021;20:795–820. doi: 10.1016/S1474-4422(21)00252-0. - DOI - PMC - PubMed
    1. Bandini F, Fontanella A, Manfellotto D et al. Quaderni dell’Italian Journal of Medicine (2020): Aggiornamenti in tema di malattia cerebrovascolare: prevenzione, terapia e riabilitazione. Vol. 8, issue 2 Mar/Apr. 10.4081/itjm.q.2020.2
    1. Decreto Ministeriale del Ministero della Salute n° 190/2003 del 24 Luglio 2003, pubblicato nella GU del 18/08/2003; last access 31.03.2022 https://www.gazzettaufficiale.it/eli/gu/2003/08/18/190/sg/pdf
    1. Italian Stroke Organization Task Force - Italian Guidelines ISO - SPREAD (Stroke Prevention and Educational Awareness Diffusion), VIII Edition. last access 31.03.2022- http://www.iso-spread.it/capitoli/LINEE_GUIDA_SPREAD_8a_EDIZIONE.pdf
    1. Determina per l’implementazione del SITS-ISTR: proseguimento dello studio post-marketing Surveillance SITS-MOST (Determinazione n. 1/AE) – GU Serie Generale n.278 del 29.11.2007 - last access 31.03.2022 https://www.gazzettaufficiale.it/eli/id/2007/11/29/07A10014/sg

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